Tumor associated glycoprotein (TAG) 72 Recombinant Antibody
Anti-Tumor associated glycoprotein (TAG) 72 [B72.3 (Satumomab)]
Reactivity
Human
Applications
Immunohistochemistry, Flow Cytometry, Functional Assay
Purity
Protein A Affinity Purified
Synonyms
Tumor associated glycoprotein (TAG) 72; Anti-Tumor associated glycoprotein (TAG) 72 [B72.3 (Satumomab)]; TAG-72; Tumor associated glycoprotein (TAG) 72 recombinant antibody
Reactivity
Human
Isotype
Rabbit IgG, kappa
Clone Number
B72.3 (Satumomab)
Specificity
Recognizes human Tumor associated glycoprotein 72.
Purity/Purification
Protein A Affinity Purified
Applicable Applications for Tumor associated glycoprotein (TAG) 72 recombinant antibody
Imaging, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS)
Application Notes
A In-111-labeled, murine version of this antibody was used in immunoscintigraphy to detect colorectal cancers in patients. In 16 % of patients, human-anti-mouse-responses developed.
Buffer Composition
PBS only with 0.02% Proclin 300.
Immunogen
Tumour-associated glycoprotein 72 is a glycoprotein found on the surface of many cancer cells, including ovary, breast, colon, and pancreatic cells.
Chimeric Use Statement
This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Preparation and Storage
Store at 4 degree C for up to 3 months. For longer storage, aliquot and store at -20 degree C.
Related Product Information for Tumor associated glycoprotein (TAG) 72 recombinant antibody
Recombinant monoclonal antibody to Tumor associated glycoprotein (TAG) 72. Manufactured using a Recombinant Platform with variable regions (i.e. specificity) from the therapeutic antibody B72.3 (Satumomab). This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Product Categories/Family for Tumor associated glycoprotein (TAG) 72 recombinant antibody
References
Abdel-Nabi et al. In-111-labeled monoclonal antibody immunoscintigraphy in colorectal carcinoma: safety, sensitivity, and preliminary clinical results. Radiology PMID:2315476
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Product Notes
The Tumor associated glycoprotein (TAG) 72 (Catalog #AAA488183) is a Recombinant Antibody and is intended for research purposes only. The product is available for immediate purchase. The Anti-Tumor associated glycoprotein (TAG) 72 [B72.3 (Satumomab)] reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Tumor associated glycoprotein (TAG) 72 can be used in a range of immunoassay formats including, but not limited to, Imaging, Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). An In-111-labeled, murine version of this antibody was used in immunoscintigraphy to detect colorectal cancers in patients. In 16 % of patients, human-anti-mouse-responses developed. Researchers should empirically determine the suitability of the Tumor associated glycoprotein (TAG) 72 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Tumor associated glycoprotein (TAG) 72, Recombinant Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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