Structure
PHTPP Biochemical
PHTPP
Purity
>98% (HPLC)
Synonyms
PHTPP; PHTPP biochemical
Purity/Purification
>98% (HPLC)
Suitability
DMSO: 14mg/mL (33mM) (<1mg/mL refers to the product slightly soluble or insoluble)
Target
Estrogen Receptor/ERR
Receptor
ERbeta
Chemical Name
4-[2-Phenyl-5, 7-bis(trifluoromethyl)pyrazolo[1, 5-a]pyrimidin-3-yl]phenol
SMILES
OC1=CC=C(C2=C3N=C(C(F)(F)F)C=C(C(F)(F)F)N3N=C2C4=CC=CC=C4)C=C1
Molecular Formula
C20H11F6N3O
CAS Number
805239-56-9
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Stability: >=2 years
Shipping: Ice Pack
Structure
Structure
Related Product Information for PHTPP biochemical
A potent, selective antagonist of estrogen ERbeta receptor; exhibits 36-fold selective for ERbeta, and is fully effective as an ERalpha antagonist, while exhibiting no significant agonism on ERbeta or Eralpha; enhances SKOV3 and OV2008 ovarian cancer cell growth in in vitro assays.
Product Categories/Family for PHTPP biochemical
References
1. Compton DR, et al. J Med Chem. 2004 Nov 18; 47 (24):5872-93.
2. Chan KK, et al. J Endocrinol. 2014 May 12; 221 (2):325-36.
3. Kajta M, et al. Neuroscience. 2013 May 15; 238:345-60.
2. Chan KK, et al. J Endocrinol. 2014 May 12; 221 (2):325-36.
3. Kajta M, et al. Neuroscience. 2013 May 15; 238:345-60.
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Product Notes
The PHTPP (Catalog #AAA3606014) is a Biochemical and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "PHTPP, Biochemical" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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