Mouse Cartilage Link Protein Monoclonal Antibody | anti-HAPLN1 antibody
Monocloncal Antibody to cartilage Link Protein (clone 8A4)
Gene Names
HAPLN1; CRTL1
Applications
Western Blot, Immunohistochemistry, immunoassay, Radioimmunoassay
Purity
Affinity purified
Synonyms
Cartilage Link Protein; Monoclonal Antibody; Monocloncal Antibody to cartilage Link Protein (clone 8A4); Antibody; Anti-HAPLN1 antibody; CRTL1; Hyaluronan and proteoglycan link protein 1; LP; Proteoglycan link protein; Cartilage-linking protein 1; HAPLN1 gene; P10915; anti-HAPLN1 antibody
Host
Mouse
Clonality
Monoclonal
Isotype
IgG
Clone Number
8A4
Specificity
This antibody recognizes the structurally related amino acid sequence epitopes … PISRP… and ….PITKP that occur in the two proteoglycan tandem repeat motifs of cartilage LP. This antibody can be used to detect intact LP 1,2 & 3 as well as a large number of smaller fragments that are generated through proteolytic cleavage during LP catabolism. It recognizes LP in all animal species from chicken to humans.
Purity/Purification
Affinity purified
Form/Format
Clear liquid; PBS, no preservatives
Concentration
0.1 mg/mL (varies by lot)
Sequence Length
354
Applicable Applications for anti-HAPLN1 antibody
Western Blot (WB), Immunohistochemistry (IHC), Radioimmunoassay (RIA)
Immunogen
Link Protein from Bovine nasal cartilage
Technical Notes
No enzyme pretreatment required, however chondroitinase and hyaluronidase will increase antibody sensitivity by exposing epitopes. For WB chondroitinase and hyaluronidase treatment is recommended.
Preparation and Storage
Store at -20 degree C.
Related Product Information for anti-HAPLN1 antibody
Cartilage-link protein (HAPLN1) monoclonal antibody (clone 8A4).
Overview: Cartilage-link protein (LP) is a glycoprotein present in cartilage that stabilizes the interaction of aggrecan (versican) with hyaluronic acid (HA) in large proteoglycan aggregates.
Overview: Cartilage-link protein (LP) is a glycoprotein present in cartilage that stabilizes the interaction of aggrecan (versican) with hyaluronic acid (HA) in large proteoglycan aggregates.
Product Categories/Family for anti-HAPLN1 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Official Full Name
cartilage link protein
NCBI Official Synonym Full Names
hyaluronan and proteoglycan link protein 1
NCBI Official Symbol
HAPLN1
NCBI Official Synonym Symbols
CRTL1
NCBI Protein Information
hyaluronan and proteoglycan link protein 1; Cartilage link protein; cartilage-link protein; cartilage linking protein 1; cartilage-linking protein 1
UniProt Protein Name
Hyaluronan and proteoglycan link protein 1
Protein Family
UniProt Gene Name
HAPLN1
UniProt Synonym Gene Names
CRTL1; Cartilage-link protein
UniProt Entry Name
HPLN1_HUMAN
Uniprot Description
Function: Stabilizes the aggregates of proteoglycan monomers with hyaluronic acid in the extracellular cartilage matrix.
Subcellular location: Secreted › extracellular space › extracellular matrix.
Tissue specificity: Widely expressed. Weakly expressed in the brain. Ref.8 Ref.9
Sequence similarities: Belongs to the HAPLN family.Contains 1 Ig-like V-type (immunoglobulin-like) domain.Contains 2 Link domains.
Research Articles on HAPLN1
Similar Products
Product Notes
The HAPLN1 hapln1 (Catalog #AAA442005) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Cartilage Link Protein can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Radioimmunoassay (RIA). Researchers should empirically determine the suitability of the HAPLN1 hapln1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Cartilage Link Protein, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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