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Goat DEFB103A/DEFB103B Polyclonal Antibody | anti-DEFB103A antibody

Goat anti-DEFB103A/DEFB103B Antibody

Gene Names
DEFB103A; BD-3; HBD3; HBP3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103
Reactivity
Expected from sequence similarity: Human
Applications
ELISA
Purity
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Synonyms
DEFB103A/DEFB103B; Polyclonal Antibody; Goat anti-DEFB103A/DEFB103B Antibody; DEFB103A; defensin; beta 103A; BD-3; DEFB-3; DEFB103; DEFB3; HBD3; HBP-3; HBP3; hBD-3; beta-defensin 103; beta-defensin 3; beta 103; beta 3; defensin-like protein; BD-3 antibody; beta-defensin 103 antibody; beta-defensin 3 antibody; DEFB103 antibody; DEFB3 antibody; DEFB-3 antibody; beta 103 antibody; beta 103A antibody; beta 3 antibody; defensin-like protein antibody; HBD3 antibody; hBD-3 antibody; HBP3 antibody; HBP-3 antibody; DEFB103A antibody; DEFB103A / DEFB103B; anti-DEFB103A antibody
Ordering
For Research Use Only!
Host
Goat
Reactivity
Expected from sequence similarity: Human
Clonality
Polyclonal
Purity/Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Form/Format
Supplied at 0.5 mg/ml in Tris saline, 0. 02% sodium azide, pH7.3 with 0.5% bovine serum albumin.
Concentration
100ug specific antibody in 200ul (varies by lot)
Sequence
PKEEQIGKCSTRGR
Sequence Length
67
Applicable Applications for anti-DEFB103A antibody
Peptide ELISA (EIA)
Application Notes
Peptide ELISA: Antibody detection limit dilution 1: 16000.
Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as small as the calculated size of 7.70kDa according to NP_001075020.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product.
Immunogen
Peptide with sequence PKEEQIGKCSTRGR, from the internal region of the protein sequence according to NP_001075020.1; NP_061131.1.
Epitope
Internal region
Preparation and Storage
Aliquot and store at -20 degree C. Minimize freezing and thawing.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
7,697 Da
NCBI Official Full Name
beta-defensin 103
NCBI Official Synonym Full Names
defensin beta 103A
NCBI Official Symbol
DEFB103A
NCBI Official Synonym Symbols
BD-3; HBD3; HBP3; DEFB3; HBP-3; hBD-3; DEFB-3; DEFB103
NCBI Protein Information
beta-defensin 103
UniProt Protein Name
Beta-defensin 103
Protein Family
UniProt Gene Name
DEFB103A
UniProt Synonym Gene Names
BD3; DEFB103; DEFB3; BD-3; DEFB-3; HBD3; hBD-3
UniProt Entry Name
D103A_HUMAN

NCBI Description

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 103, an antibiotic peptide which is induced by bacteria and interferon gamma, and which displays antimicrobial activity against S. aureus, S. pyogenes, P. aeruginosa, E. coli, and C. albicans. [provided by RefSeq, Oct 2014]

Uniprot Description

defensin, beta 3: Exhibits antimicrobial activity against Gram-positive bacteria S.aureus and S.pyogenes, Gram-negative bacteria P.aeruginosa and E.coli and the yeast C.albicans. Kills multiresistant S.aureus and vancomycin-resistant E.faecium. No significant hemolytic activity was observed. Belongs to the beta-defensin family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 8p23.1

Cellular Component: extracellular region; extracellular space; Golgi lumen

Biological Process: defense response to bacterium; innate immune response; positive regulation of biosynthetic process of antibacterial peptides active against Gram-positive bacteria

Research Articles on DEFB103A

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Product Notes

The DEFB103A defb103a (Catalog #AAA422808) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-DEFB103A/DEFB103B Antibody reacts with Expected from sequence similarity: Human and may cross-react with other species as described in the data sheet. AAA Biotech's DEFB103A/DEFB103B can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA). Peptide ELISA: Antibody detection limit dilution 1: 16000. Western Blot: Not yet tested - our routinely used western blotting protocol does not allow detection of proteins as small as the calculated size of 7.70kDa according to NP_001075020.1. Therefore we cannot recommend an optimal concentration and the antibody is an aspiring product. Researchers should empirically determine the suitability of the DEFB103A defb103a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: PKEEQIGKCS TRGR. It is sometimes possible for the material contained within the vial of "DEFB103A/DEFB103B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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