CTBP2 recombinant protein

Recombinant CTBP2 protein

Cat. Num. AAA389300

• Synonyms: CTBP2; Recombinant CTBP2 protein; C-terminal binding protein 2; CTBP2 recombinant protein

• Host: E Coli
• Form/Format: Recombinant CTBP2 protein is supplied in 25mM Tris-HCl pH8.0, 500mM NaCl, 10% glycerol, 0.5mM TCEP.

• Protein Species: Human
• Tag: His-Tag
• Protein Details: Recombinant CTBP2 protein was expressed in E Coli as the full length protein (accession number NP_001320.1) with an N-terminal 6xHis-tag.
• Notes: This product was manufactured as described in Protein Details. Where possible, We has developed functional or activity assays for recombinant proteins. Additional characterization such as enzyme kinetic activity assays, inhibitor screening or other biological activity assays may not have been performed for every product. All available data for this product is shown.
• Dry Ice Shipment: Extra charge fee may add to your shipping cost as dry ice is required to ship this product.
• Preparation and Storage: Recombinant proteins in solution are temperature sensitive and must be stored at -80 degree C to prevent degradation. Avoid repeated freeze/thaw cycles and keep on ice when not in storage.; Shipping Temp: Dry Ice

SDS-Page

(Recombinant CTBP2 protein 10% SDS-PAGE Coomassie staining MW: 52.5 kDa Purity: >90%)

Related Product Information for CTBP2 recombinant protein

Short Description: CTBP2 (C-Terminal Binding Protein 2), also written as CtBP2, is a protein that binds to the C-terminus of adenovirus E1A proteins. It ubiquitously expresses with 2 higher level in heart, skeletal muscle, pancreas, associating to adenovirus E1A,C terminal proteins, involved with histone deacetylase and E2F3 in transcription repression. CTBP2 is a corepressor targeting diverse transcription regulators. It functions in brown adipose tissue (BAT) differentiation (By similarity). CTBP1 gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This product is isoform 1. CTBP2 and another C-Terminal Binding Protein, CTBP1 can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development.

Background: CTBP2 (C-Terminal Binding Protein 2), also written as CtBP2, is a protein that binds to the C-terminus of adenovirus E1A proteins. It ubiquitously expresses with 2 higher level in heart, skeletal muscle, pancreas, associating to adenovirus E1A, C terminal proteins, involved with histone deacetylase and E2F3 in transcription repression. CTBP2 is a corepressor targeting diverse transcription regulators. It functions in brown adipose tissue (BAT) differentiation (By similarity). CTBP1 gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. This product is isoform 1. CTBP2 and another C-Terminal Binding Protein, CTBP1 can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development.

Product Categories/Family for CTBP2 recombinant protein

Recombinant Proteins; Transcription

NCBI and Uniprot Product Information

• Molecular Weight: Molecular weight of the protein is 52.5kDa
• Protein Family: C-terminal-binding protein