Rat Eukaryotic elongation factor 2 kinase ELISA Kit | Eef2k elisa kit
Rat Eukaryotic elongation factor 2 kinase ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
catalyzes the phosphorylation of eukaryotic elongation factor 2 (eEF2) [RGD, Feb 2006]
Uniprot Description
EEF2K: an atypical protein kinase of the Alpha family. Dependent on Ca2 ions and calmodulin. May play a key role linking cellular energy status and the inhibition of protein synthesis, a major consumer of metabolic energy. Phosphorylates and inactivates eEF2, resulting in the inhibition of peptide-chain elongation eEF2K is phosphorylated and activated by AMPK in response to elevated AMP levels, which increase during cellular stress and starvation. Regulated in response to a range of stimuli including TNF-alpha. Overexpressed in breast cancer cell lines and tumors. Activated in rat glioblastoma, and growth was inhibited by the drug Rottlerin. Activity induced in ischemic heart muscle
Protein type: Kinase, protein; Translation; Protein kinase, Ser/Thr (non-receptor); Protein kinase, atypical; EC 2.7.11.20; ATYPICAL group; Alpha family; eEF2K subfamily
Cellular Component: postsynaptic density
Molecular Function: ATP binding; calcium ion binding; calmodulin binding; elongation factor-2 kinase activity
Biological Process: cellular response to insulin stimulus; negative regulation of apoptosis; positive regulation of endocytosis; positive regulation of synaptogenesis; protein amino acid autophosphorylation; regulation of protein amino acid autophosphorylation
Research Articles on Eef2k
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Product Notes
The Rat Eef2k eef2k (Catalog #AAA2880619) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2880619 ELISA Kit recognizes Rat Eef2k. It is sometimes possible for the material contained within the vial of "Eukaryotic elongation factor 2 kinase, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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