NKG2A / NKG2 / CD159A / KLRC1 recombinant protein
Recombinant Mouse NKG2A / NKG2 / CD159A / KLRC1 Protein (His tag)
Gene Names
Klrc1; NKG2A; NKG2B; CD159a
Purity
> 95 % as determined by SDS-PAGE
Synonyms
NKG2A / NKG2 / CD159A / KLRC1; Recombinant Mouse NKG2A / NKG2 / CD159A / KLRC1 Protein (His tag); Klrc1; Nkg2a; NKG2A / NKG2 / CD159A / KLRC1 recombinant protein
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Sequence Length
244
Application Notes
The recombinant mouse Klrc1 consists of 171 amino acids and predicts a molecular mass of 19.6 KDa. It migrates as an approximately 33-40 KDa band in SDS-PAGE under reducing conditions.
Predicted N Terminal
His
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C
Related Product Information for NKG2A / NKG2 / CD159A / KLRC1 recombinant protein
Background: NKG2, also known as NKG2A (CD159A), is a member of the killer cell lectin-like receptor family. This family is a group of transmembrane proteins preferentially expressed in NK cells. Members of this fmaily are characterized by the type II membrane orientation and the presence of a C-type lectin domain. NKG2 contains 1 C-type lectin domain and forms a complex with another family member, KLRD1/CD94. It is expressed only in NK-cells, but not in T-cells or B-cells. It has been shown that NKG2 represents a family of related cDNA clones, designated NKG2A, NKG2B, NKG2C, and NKG2D, which encode type 2 integral membrane proteins (extracellular C-terminus) containing a C-type lectin domain. Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. NKG2 functions as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells.
Description: A DNA sequence encoding the mouse Klrc1 (AAD24969.1) (Ala94-Ile244) was expressed with a polyhistidine tag at the N-terminus.
Description: A DNA sequence encoding the mouse Klrc1 (AAD24969.1) (Ala94-Ile244) was expressed with a polyhistidine tag at the N-terminus.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
27,606 Da
NCBI Official Full Name
natural killer cell receptor NKG2A
NCBI Official Synonym Full Names
killer cell lectin-like receptor subfamily C, member 1
NCBI Official Symbol
Klrc1
NCBI Official Synonym Symbols
NKG2A; NKG2B; CD159a
NCBI Protein Information
NKG2-A/NKG2-B type II integral membrane protein
UniProt Protein Name
Natural killer cell receptor NKG2A
UniProt Gene Name
Klrc1
Research Articles on NKG2A / NKG2 / CD159A / KLRC1
Similar Products
Product Notes
The NKG2A / NKG2 / CD159A / KLRC1 klrc1 (Catalog #AAA2546764) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant mouse Klrc1 consists of 171 amino acids and predicts a molecular mass of 19.6 KDa. It migrates as an approximately 33-40 KDa band in SDS-PAGE under reducing conditions. Researchers should empirically determine the suitability of the NKG2A / NKG2 / CD159A / KLRC1 klrc1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "NKG2A / NKG2 / CD159A / KLRC1, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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