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Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47431(PAM16 Antibody) at dilution 1/50.(Original magnification: 200))

Rabbit anti-Human, Mouse PAM16 Polyclonal Antibody | anti-PAM16 antibody

PAM16 Antibody

Gene Names
PAM16; TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136
Reactivity
Human, Mouse
Applications
Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
PAM16; Polyclonal Antibody; PAM16 Antibody; TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136; anti-PAM16 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Specificity
The antibody detects endogenous levels of total PAM16 protein.
Purity/Purification
Antigen affinity purification
Form/Format
pH 7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration
0.9 mg/mL (varies by lot)
Sequence Length
125
Applicable Applications for anti-PAM16 antibody
Immunohistochemistry (IHC)
Application Notes
IHC: 1:50-200
Immunogen
Fusion protein of human PAM16
Immunogen Type
Peptide
Preparation and Storage
Store at -20 degree C.

Immunohistochemistry (IHC)

(The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47431(PAM16 Antibody) at dilution 1/50.(Original magnification: 200))

Immunohistochemistry (IHC) (The image is immunohistochemistry of paraffin-embedded Human cervical cancer tissue using 47431(PAM16 Antibody) at dilution 1/50.(Original magnification: 200))
Related Product Information for anti-PAM16 antibody
This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities.
Product Categories/Family for anti-PAM16 antibody

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
13,825 Da
NCBI Official Full Name
mitochondrial import inner membrane translocase subunit TIM16
NCBI Official Synonym Full Names
presequence translocase associated motor 16
NCBI Official Symbol
PAM16
NCBI Official Synonym Symbols
TIM16; MAGMAS; SMDMDM; TIMM16; CGI-136
NCBI Protein Information
mitochondrial import inner membrane translocase subunit TIM16
UniProt Protein Name
Mitochondrial import inner membrane translocase subunit TIM16
UniProt Gene Name
PAM16
UniProt Synonym Gene Names
MAGMAS; TIM16; TIMM16

NCBI Description

This gene encodes a mitochondrial protein involved in granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling. This protein also plays a role in the import of nuclear-encoded mitochondrial proteins into the mitochondrial matrix and may be important in reactive oxygen species (ROS) homeostasis. Mutations in this gene cause Megarbane-Dagher-Melike type spondylometaphyseal dysplasia, an early lethal skeletal dysplasia characterized by short stature, developmental delay and other skeletal abnormalities. [provided by RefSeq, May 2017]

Uniprot Description

Regulates ATP-dependent protein translocation into the mitochondrial matrix. Inhibits DNAJC19 stimulation of HSPA9/Mortalin ATPase activity.

Research Articles on PAM16

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Product Notes

The PAM16 pam16 (Catalog #AAA9430413) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PAM16 Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PAM16 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC). IHC: 1:50-200. Researchers should empirically determine the suitability of the PAM16 pam16 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PAM16, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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