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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CCL6 Polyclonal Antibody at dilution 1:50)

Rabbit anti-Human, Mouse CCL6 Polyclonal Antibody | anti-CCL6 antibody

CCL6 Polyclonal Antibody

Gene Names
Ccl6; c10; MRP-1; Scya6
Reactivity
Human, Mouse
Applications
ELISA, Immunohistochemistry
Purity
Affinity purification
Synonyms
CCL6; Polyclonal Antibody; CCL6 Polyclonal Antibody; C10; Scya6; MRP-1; anti-CCL6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Affinity purification
Form/Format
PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Applicable Applications for anti-CCL6 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:25-1:100
Immunogen
Synthetic peptide of mouse CCL6
Note
Centrifuge before opening to ensure complete recovery of vial contents.
Preparation and Storage
Store at -20 degree C. Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CCL6 Polyclonal Antibody at dilution 1:50)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human lung cancer tissue using CCL6 Polyclonal Antibody at dilution 1:50)
Related Product Information for anti-CCL6 antibody
In mice, Ccl6 is expressed in cells from neutrophil and macrophage lineages, and can be greatly induced under conditions suitable for myeloid cell differentiation. It is highly expressed in bone marrow cultures that have been stimulated with the cytokine GM-CSF. Some low levels of gene expression also occur in certain cell lines of myeloid origin (e.g. the immature myeloid cell lines DA3 and 32D cl3, and the macrophage cell line P388D) that can also be greatly induced in culture with GM-CSF. However, in activated T cell lines, expression of Ccl6 is greatly reduced. Ccl6 can also be induced in the mouse lung by the cytokine interleukin 13.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
NCBI Official Full Name
C-C motif chemokine 6
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 6
NCBI Official Symbol
Ccl6
NCBI Official Synonym Symbols
c10; MRP-1; Scya6
NCBI Protein Information
C-C motif chemokine 6; CC chemokine C10; small inducible cytokine A6; small-inducible cytokine A6
UniProt Protein Name
C-C motif chemokine 6
Protein Family
UniProt Gene Name
Ccl6
UniProt Synonym Gene Names
C10; Scya6
UniProt Entry Name
CCL6_MOUSE

Uniprot Description

CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Motility/polarity/chemotaxis

Cellular Component: extracellular space; extracellular region

Molecular Function: chemokine activity; cytokine activity

Biological Process: immune response; chemotaxis

Research Articles on CCL6

Similar Products

Product Notes

The CCL6 ccl6 (Catalog #AAA2529419) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The CCL6 Polyclonal Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's CCL6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:25-1:100. Researchers should empirically determine the suitability of the CCL6 ccl6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "CCL6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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