Testing Data
C-10 Active Protein | C10 active protein
Murine C-10 (CCL6)
Gene Names
Ccl6; c10; MRP-1; Scya6
Reactivity
Species Reactivity: Mouse
Purity
Above 98% as determined by SDS-PAGE Analysis.
Synonyms
C-10; Murine C-10 (CCL6); Recombinant Murine C10 (CCL6); C10 active protein
Host
E Coli
Reactivity
Species Reactivity: Mouse
Purity/Purification
Above 98% as determined by SDS-PAGE Analysis.
Sequence
GLIQEIEKE DRRYNPPII HQGFQDTSS DCCFSYATQ IPCKRFIYY FPTSGGCIK PGIIFISRR GTQVCADPS DRRVQRCLS TLKQGPRSG NKVIA
Biological Activity
Determined by its ability to chemoattract Balb/c mouse spleen MNCs using a concentration range of 10.0-100.0 ng/ml.
Preparation and Storage
At -20 degree C
Testing Data
Testing Data
Related Product Information for C10 active protein
Murine C10 belongs to the CC chemokine family and is expressed in myelopoietic bone marrow cultures when stimulated with GM-CSF, M-CSF, IL-3 or IL-4. It signals primarily through the CCR1 receptor. C10 is chemotactic for B cells, CD4+ T cells, monocytes and NK cells and also exhibits powerful suppressive activity on colony formation by different lineages of hematopoietic progenitors. The C10 contains the four highly conserved cysteine residues present in CC chemokines. The mature protein contains 95 amino acid residues. Recombinant murine C-10 is a 10.7 kDa protein containing 95 amino acid residues.
Product Categories/Family for C10 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
12,984 Da
NCBI Official Full Name
C-C motif chemokine 6
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 6
NCBI Official Symbol
Ccl6
NCBI Official Synonym Symbols
c10; MRP-1; Scya6
NCBI Protein Information
C-C motif chemokine 6; CC chemokine C10; small inducible cytokine A6; small-inducible cytokine A6
UniProt Protein Name
C-C motif chemokine 6
Protein Family
UniProt Gene Name
Ccl6
UniProt Synonym Gene Names
C10; Scya6
UniProt Entry Name
CCL6_MOUSE
Uniprot Description
CCL6: Shows chemotactic activity for monocytes, resting T- lymphocytes, and neutrophils, but not for activated lymphocytes. Inhibits proliferation of myeloid progenitor cells in colony formation assays. This protein can bind heparin. Binds CCR1. CCL23(19-99), CCL23(22-99), CCL23(27-99), CCL23(30-99) are more potent chemoattractants than the small-inducible cytokine A23. Belongs to the intercrine beta (chemokine CC) family. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted
Cellular Component: extracellular space; extracellular region
Molecular Function: chemokine activity; cytokine activity
Biological Process: immune response; chemotaxis
Research Articles on C10
Similar Products
Product Notes
The C10 ccl6 (Catalog #AAA695783) is an Active Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The Murine C-10 (CCL6) reacts with Species Reactivity: Mouse and may cross-react with other species as described in the data sheet. The amino acid sequence is listed below: GLIQEIEKE DRRYNPPII HQGFQDTSS DCCFSYATQ IPCKRFIYY FPTSGGCIK PGIIFISRR GTQVCADPS DRRVQRCLS TLKQGPRSG NKVIA. It is sometimes possible for the material contained within the vial of "C-10, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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