Typical Testing Data/Standard Curve (for reference only)
Rabbit ADCY1 ELISA Kit | ADCY1 elisa kit
Rabbit ADCY1 (Adenylate Cyclase 1, Brain) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principle of the Assay: This ELISA kit uses Sandwich-ELISA as the method. The micro ELISA plate provided in this kit has been pre-coated with an antibody specific to ADCY1. Standards or samples are added to the appropriate micro ELISA plate wells and combined with the specific antibody. Then a biotinylated detection antibody specific for ADCY1 and Avidin-Horseradish Peroxidase (HRP) conjugate is added to each micro plate well successively and incubated. Free components are washed away. The substrate solution is added to each well. Only those wells that contain ADCY1, biotinylated detection antibody and Avidin-HRP conjugate will appear blue in color. The enzyme-substrate reaction is terminated by the addition of a sulphuric acid solution and the color turns yellow. The optical density (OD) is measured spectrophotometrically at a wavelength of 450 nm +/- 2 nm. The OD value is proportional to the concentration of ADCY1. You can calculate the concentration of ADCY1 in the samples by comparing the OD of the samples to the standard curve.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
Uniprot Description
ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.
Protein type: Nucleotide Metabolism - purine; EC 4.6.1.1; Transporter, aquaporin family; Membrane protein, integral; Lyase; Adenylyl cyclase; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 7p12.3
Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus
Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding
Biological Process: epidermal growth factor receptor signaling pathway; circadian rhythm; response to drug; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; response to lithium ion; water transport; activation of protein kinase A; signal transduction; regulation of circadian rhythm; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; long-term memory; axonogenesis; phospholipase C activation; energy reserve metabolic process; renal water homeostasis; innate immune response; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport
Disease: Deafness, Autosomal Recessive 44
Research Articles on ADCY1
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Product Notes
The Rabbit ADCY1 adcy1 (Catalog #AAA2515348) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2515348 ELISA Kit recognizes Rabbit ADCY1. It is sometimes possible for the material contained within the vial of "ADCY1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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