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Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ADCY1 Polyclonal Antibody at dilution 1:60)

Rabbit ADCY1 Polyclonal Antibody | anti-ADCY1 antibody

ADCY1 Polyclonal Antibody

Gene Names
ADCY1; AC1; DFNB44
Reactivity
Human, Mouse, Rat
Applications
ELISA, Immunohistochemistry
Purity
Antigen affinity purification
Synonyms
ADCY1; Polyclonal Antibody; ADCY1 Polyclonal Antibody; AC1; anti-ADCY1 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Isotype
IgG
Purity/Purification
Antigen affinity purification
Concentration
2.7mg/mL (varies by lot)
Sequence Length
338
Applicable Applications for anti-ADCY1 antibody
ELISA (EIA), Immunohistochemistry (IHC)
Application Notes
IHC: 1:100-1:300
Immunogen
Synthetic peptide of human ADCY1
Buffer
PBS with 0.05% sodium azide, 50% glycerol, pH7.3
Preparation and Storage
Store at -20 degree C (regular) and -80 degree C (long term). Avoid freeze / thaw cycles.

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ADCY1 Polyclonal Antibody at dilution 1:60)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human colon cancer tissue using ADCY1 Polyclonal Antibody at dilution 1:60)

Immunohistochemistry (IHC)

(Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ADCY1 Polyclonal Antibody at dilution 1:60)

Immunohistochemistry (IHC) (Immunohistochemistry of paraffin-embedded Human liver cancer tissue using ADCY1 Polyclonal Antibody at dilution 1:60)
Related Product Information for anti-ADCY1 antibody
This gene encodes a form of adenylate cyclase expressed in brain. A similar protein in mouse is involved in pattern formation of the brain.

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
107
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
123,440 Da
NCBI Official Full Name
adenylate cyclase type 1 isoform 2
NCBI Official Synonym Full Names
adenylate cyclase 1 (brain)
NCBI Official Symbol
ADCY1
NCBI Official Synonym Symbols
AC1; DFNB44
NCBI Protein Information
adenylate cyclase type 1; 3',5'-cyclic AMP synthetase; ATP pyrophosphate-lyase 1; Ca(2+)/calmodulin-activated adenylyl cyclase; adenyl cyclase; adenylate cyclase type I; adenylyl cyclase 1
UniProt Protein Name
Adenylate cyclase type 1
Protein Family
UniProt Gene Name
ADCY1
UniProt Entry Name
ADCY1_HUMAN

NCBI Description

This gene encodes a member of the of adenylate cyclase gene family that is primarily expressed in the brain. This protein is regulated by calcium/calmodulin concentration and may be involved in brain development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

Uniprot Description

ADCY1: a calmodulin-sensitive adenylyl cyclase expressed in brain. The mouse protein is involved in pattern formation of the brain. May be involved in regulatory processes in the central nervous system. It may play a role in memory acquisition and learning.

Protein type: Membrane protein, integral; Nucleotide Metabolism - purine; EC 4.6.1.1; Membrane protein, multi-pass; Adenylyl cyclase; Transporter; Transporter, aquaporin family; Lyase

Chromosomal Location of Human Ortholog: 7p12.3

Cellular Component: cytoplasm; integral to membrane; plasma membrane; nucleus

Molecular Function: calmodulin binding; metal ion binding; calcium- and calmodulin-responsive adenylate cyclase activity; ATP binding

Biological Process: epidermal growth factor receptor signaling pathway; response to drug; circadian rhythm; fibroblast growth factor receptor signaling pathway; nerve growth factor receptor signaling pathway; response to lithium ion; water transport; activation of protein kinase A; regulation of circadian rhythm; signal transduction; G-protein signaling, adenylate cyclase activating pathway; synaptic transmission; long-term memory; axonogenesis; phospholipase C activation; energy reserve metabolic process; innate immune response; renal water homeostasis; cAMP biosynthetic process; G-protein signaling, adenylate cyclase inhibiting pathway; transmembrane transport

Disease: Deafness, Autosomal Recessive 44

Research Articles on ADCY1

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Product Notes

The ADCY1 adcy1 (Catalog #AAA2525281) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ADCY1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's ADCY1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC). IHC: 1:100-1:300. Researchers should empirically determine the suitability of the ADCY1 adcy1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "ADCY1, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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