Rabbit SH3RF2 Polyclonal Antibody | anti-SH3RF2 antibody

Rabbit Polyclonal to Human SH3RF2

Cat. Num. AAA244186

• Gene Names: SH3RF2; HEPP1; POSHER; RNF158; PPP1R39
• Reactivity: Human, Mouse, Rat
• Applications: Immunohistochemistry, Western Blot, ELISA
• Purity: Immunoaffinity Purified
• Synonyms: SH3RF2; Polyclonal Antibody; Rabbit Polyclonal to Human SH3RF2; Anti-SH3RF2 Antibody (C-Terminus) IHC-plus; HEPP1; PPP1R39; POSH-eliminating RING protein; RING finger protein 158; RNF158; POSHER; Human SH3RF2; anti-SH3RF2 antibody

• Host: Rabbit
• Reactivity: Human, Mouse, Rat
• Clonality: Polyclonal
• Specificity: Human SH3RF2
• Purity/Purification: Immunoaffinity Purified
• Form/Format: PBS, 0.02% sodium azide
• Concentration: 1 mg/ml (varies by lot)
• Sequence Length: 180915260

• Applicable Applications for anti-SH3RF2 antibody: Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA)
• Application Notes: ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml); Usage: SH3RF2 antibody can be used for detection of SH3RF2 by Western blot at 1-2 ug/ml.
• Target Species: Human
• Immunogen Description: A 17 amino acid peptide near the carboxy terminus of human SH3RF2.
• Immunogen Type: Synthetic peptide
• Immunogen: SH3RF2 antibody was raised against a 17 amino acid peptide near the carboxy terminus of human SH3RF2.
• Antigen Modification: C-Terminus
• Preparation and Storage: Short term 4 degree C, long term aliquot and store at -20 degree C, avoid freeze thaw cycles. Store undiluted.

Immunohistochemistry (IHC)

(Anti-SH3RF2 antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunohistochemistry (IHC)

(Anti-SH3RF2 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)

Immunofluorescence (IF)

(Immunofluorescence of SH3RF2 in human brain tissue with SH3RF2 antibody at 20 ug/ml.)

Western Blot (WB)

(Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 ug/ml.)

NCBI and Uniprot Product Information

• NCBI GI #: 224589817
• NCBI GeneID: 153769
• NCBI Accession #: NC_000005.9
• NCBI GenBank Nucleotide #: NC_000005.9
• Molecular Weight: 19,895 Da
• NCBI Official Full Name: Homo sapiens chromosome 5, GRCh37.p13 Primary Assembly
• NCBI Official Synonym Full Names: SH3 domain containing ring finger 2
• NCBI Official Symbol: SH3RF2
• NCBI Official Synonym Symbols: HEPP1; POSHER; RNF158; PPP1R39
• NCBI Protein Information: putative E3 ubiquitin-protein ligase SH3RF2; RING finger protein 158; POSH-eliminating RING protein; SH3 domain-containing RING finger protein 2; heart protein phosphatase 1-binding protein; protein phosphatase 1 regulatory subunit 39; protein phosphatase 1, regulatory subunit 39
• UniProt Protein Name: Putative E3 ubiquitin-protein ligase SH3RF2
• Protein Family: Putative E3 ubiquitin-protein ligase
• UniProt Gene Name: SH3RF2
• UniProt Synonym Gene Names: PPP1R39; RNF158; HEPP1
• UniProt Entry Name: SH3R2_HUMAN

Uniprot Description

SH3RF2: Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function. Belongs to the SH3RF family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Ubiquitin ligase; EC 6.3.2.-; Ligase; Ubiquitin conjugating system

Chromosomal Location of Human Ortholog: 5q32

Cellular Component: nucleoplasm

Molecular Function: protein binding; zinc ion binding; protein phosphatase inhibitor activity; protein phosphatase 1 binding; phosphatase binding; ligase activity

Biological Process: protein ubiquitination