Western Blot (WB)
(Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 ug/mL.)
Rabbit SH3RF2 Polyclonal Antibody | anti-SH3RF2 antibody
SH3RF2 Antibody
Gene Names
SH3RF2; HEPP1; POSHER; RNF158; PPP1R39
Reactivity
Human, Mouse, Rat
Applications
ELISA, Western Blot, Immunohistochemistry
Purity
Affinity chromatography purified via peptide column
Synonyms
SH3RF2; Polyclonal Antibody; SH3RF2 Antibody; SH3 domain containing ring finger 2; heart protein phosphatase 1-binding protein; Hepp1; FLJ23654; anti-SH3RF2 antibody
Host
Rabbit
Reactivity
Human, Mouse, Rat
Clonality
Polyclonal
Purity/Purification
Affinity chromatography purified via peptide column
Form/Format
Supplied in PBS containing 0.02% sodium azide.
Sequence Length
729
Applicable Applications for anti-SH3RF2 antibody
ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC)
Immunogen Type
Peptide
Immunogen Description
Raised against a 17 amino acid peptide near the carboxy terminus of human SH3RF2.
Target Name
SH3RF2
Preparation and Storage
Can be stored at -20 degree C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Western Blot (WB)
(Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 ug/mL.)
Western Blot (WB)
(Western blot analysis of SH3RF2 in 3T3 cell lysate with SH3RF2 antibody at (A) 1 and (B) 2 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SH3RF2 in human brain tissue with SH3RF2 antibody at 10 ug/mL.)
Immunohistochemistry (IHC)
(Immunohistochemistry of SH3RF2 in human brain tissue with SH3RF2 antibody at 10 ug/mL.)
Related Product Information for anti-SH3RF2 antibody
Although the SH3 domain containing ring finger 2 protein (SH3RF2) has been identified as a marker of the nucleus accumbens in the human brain, little is known about this protein. Recent yeast two-hybrid experiments have shown that SH3RF2 associates with protein phosphatase 1 (PP1) and is expressed primarily in heart and testis tissue. Recombinant SH3RF2 enhanced PP1 enzymatic activity and antagonized the ability of phopho-inhibitor-1 or -2 to inhibit PP1, suggesting that SH3RF2 may play a role working with PP1 in cardiac functions.
Product Categories/Family for anti-SH3RF2 antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19,895 Da
NCBI Official Full Name
putative E3 ubiquitin-protein ligase SH3RF2
NCBI Official Synonym Full Names
SH3 domain containing ring finger 2
NCBI Official Symbol
SH3RF2
NCBI Official Synonym Symbols
HEPP1; POSHER; RNF158; PPP1R39
NCBI Protein Information
putative E3 ubiquitin-protein ligase SH3RF2
UniProt Protein Name
Putative E3 ubiquitin-protein ligase SH3RF2
Protein Family
UniProt Gene Name
SH3RF2
UniProt Synonym Gene Names
PPP1R39; RNF158; HEPP1
UniProt Entry Name
SH3R2_HUMAN
Uniprot Description
SH3RF2: Inhibits PPP1CA phosphatase activity. May be a E3 ubiquitin-protein ligase (Potential). May play a role in cardiac function. Belongs to the SH3RF family. 3 isoforms of the human protein are produced by alternative splicing.
Protein type: EC 6.3.2.-; Ubiquitin conjugating system; Ubiquitin ligase; Ligase
Chromosomal Location of Human Ortholog: 5q32
Cellular Component: nucleoplasm
Molecular Function: protein binding; zinc ion binding; protein phosphatase inhibitor activity; protein phosphatase 1 binding; phosphatase binding; ligase activity
Biological Process: protein ubiquitination
Research Articles on SH3RF2
Similar Products
Product Notes
The SH3RF2 sh3rf2 (Catalog #AAA9401333) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The SH3RF2 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. AAA Biotech's SH3RF2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the SH3RF2 sh3rf2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "SH3RF2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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