Interleukin-21 Recombinant Protein | IL21 recombinant protein

Recombinant Bovine Interleukin-21

Cat. Num. AAA225394

• Reactivity: Bovine
• Applications: ELISA, Western Blot
• Purity: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Synonyms: Interleukin-21; Recombinant Bovine Interleukin-21; IL-21; IL21 recombinant protein

• Host: Pichia pastoris
• Reactivity: Bovine
• Purity/Purification: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Form/Format: Lyophilized in phosphate buffered saline with 10% Trahalose.
• Sequence Length: 146

• Applicable Applications for IL21 recombinant protein: ELISA (EIA), Western Blot (WB)
• Reconstitution: Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommend that the vial is gently mixed after reconstitution.
• Preparation and Storage: Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.; Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 12 months from date of despatch

ELISA (EIA)

(Bovine interleukin-21 ELISA Recombinant Bovine interleukin-21 detected using Rabbit anti Bovine interleukin-21 as the capture reagent and Rabbit anti Bovine interleukin-21:Biotin as the detection reagent followed by Streptavidin:HRP)

Related Product Information for IL21 recombinant protein

Recombinant Bovine interleukin-21 (IL-21) is a recombinant protein corresponding to aa 18-146 of native bovine IL-21.

Bovine interleukin-21 is a potent type I regulatory cytokine belonging to the IL-15/IL-21 family expressed by activated T-cells. Interleukin-21 is involved with the modulation of T and B cell activity along with promoting proliferation of NK cells and cytotoxic T-cells.

NCBI and Uniprot Product Information

• NCBI GI #: 55976465
• NCBI GeneID: 378475
• UniProt Accession #: Q76LU5
• Molecular Weight: 15.1 kDa
• NCBI Official Full Name: Interleukin-21
• NCBI Official Synonym Full Names: interleukin 21
• NCBI Official Symbol: IL21
• NCBI Protein Information: interleukin-21
• UniProt Protein Name: Interleukin-21
• Protein Family: Interleukin
• UniProt Gene Name: IL21
• UniProt Synonym Gene Names: IL-21

Uniprot Description

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells. May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells (). During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation ().