Interleukin-17 Recombinant Protein | IL-17A recombinant protein

Recombinant Dog Interleukin-17

Cat. Num. AAA225408

• Gene Names: IL17A; IL17; CTLA8; IL-17; CTLA-8; IL-17A
• Reactivity: Dog
• Applications: ELISA, Western Blot
• Purity: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Synonyms: Interleukin-17; Recombinant Dog Interleukin-17; IL-17A; IL-17A recombinant protein

• Host: Pichia pastoris
• Reactivity: Dog
• Purity/Purification: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Form/Format: Lyophilized in phosphate buffered saline with 10% Trahalose.
• Sequence Length: 9

• Applicable Applications for IL-17A recombinant protein: ELISA (EIA), Western Blot (WB)
• Reconstitution: Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommend that the vial is gently mixed after reconstitution.
• Preparation and Storage: Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.; Storage in frost-free freezers is not recommended. This product should be stored undiluted. Avoid repeated freezing and thawing as this may denature the protein. Shelf Life: 12 months from date of despatch

ELISA (EIA)

(Dog Interleukin-17A ELISA: Recombinant Dog interleukin-17A (PDP016) detected using Rabbit anti Dog interleukin-17A as the capture reagent and Rabbit anti Dog interleukin-17A:Biotin as the detection reagent followed by Streptavidin:HRP)

Related Product Information for IL-17A recombinant protein

Recombinant Dog interleukin-17A (IL-17A) is a recombinant protein corresponding to a 127 amino acid sequence of native canine IL-17A.Native canine IL-17A is a 17.7 kDa proinflammatory cytokine belonging to the IL-17 cytokine family and produced by activated T cells.

NCBI and Uniprot Product Information

• NCBI GI #: 55139064
• NCBI GeneID: 3605
• Molecular Weight: 14.8 kDa
• NCBI Official Full Name: interleukin-17, partial
• NCBI Official Synonym Full Names: interleukin 17A
• NCBI Official Symbol: IL17A
• NCBI Official Synonym Symbols: IL17; CTLA8; IL-17; CTLA-8; IL-17A
• NCBI Protein Information: interleukin-17A
• UniProt Protein Name: Interleukin-17A
• Protein Family: Interleukin
• UniProt Gene Name: IL17A
• UniProt Synonym Gene Names: CTLA8; IL17; IL-17; IL-17A; CTLA-8

NCBI Description

The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cytokine are associated with several chronic inflammatory diseases including rheumatoid arthritis, psoriasis and multiple sclerosis. [provided by RefSeq, Jul 2008]

Uniprot Description

Ligand for IL17RA and IL17RC (PubMed:17911633). The heterodimer formed by IL17A and IL17F is a ligand for the heterodimeric complex formed by IL17RA and IL17RC (PubMed:18684971). Involved in inducing stromal cells to produce proinflammatory and hematopoietic cytokines (PubMed:8676080).