Interleukin-4 Recombinant Protein | IL4 recombinant protein

Recombinant Rabbit Interleukin-4

Cat. Num. AAA225430

• Gene Names: IL4; IL2; BSF-1
• Reactivity: Rabbit
• Applications: ELISA
• Purity: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Synonyms: Interleukin-4; Recombinant Rabbit Interleukin-4; IL-4; IL4 recombinant protein

• Host: Pichia pastoris
• Reactivity: Rabbit
• Purity/Purification: >95% by SDS PAGE analysis; Purified by ion-exchange chromatography
• Form/Format: Lyophilized in phosphate buffered saline with 10% Trahalose.
• Sequence Length: 147

• Applicable Applications for IL4 recombinant protein: ELISA (EIA)
• Reconstitution: Reconstitute with 20 ul sterile PBS containing 0.1% carrier protein. Care should be taken during reconstitution as the protein may appear as a film at the bottom of the vial. It is recommend that the vial is gently mixed after reconstitution.
• Preparation and Storage: Prior to reconstitution store at -20 degree C. After reconstitution store at -20 degree C.; Storage in frost-free freezers is not recommended. This product should be stored undiluted. Shelf Life: 12 months from date of despatch

ELISA (EIA)

(Rabbit Interleukin-4 ELISA: Recombinant Rabbit interleukin-4 detected using Goat anti Rabbit interleukin-4 as the capture reagent and Goat anti Rabbit interleukin-4:Biotin as the detection reagent followed by Streptavidin:HRP)

Related Product Information for IL4 recombinant protein

Recombinant Rabbit interleukin-4 is a recombinant protein corresponding to aa 24 - 147 of rabbit interleukin-4 (IL-4), a 16.6 kDa regulatory cytokine belonging to the IL-4 / IL-13 family. IL-4 is expressed by a range of cells including B cells, macrophages and monocytes. It plays an important role in the regulation of rabbit B cell responses, is involved in promoting secretion and cell surface expression of IgG1 and IgE, and with the regulation of CD23 expression on lymphocytes and monocytes.

NCBI and Uniprot Product Information

• NCBI GI #: 75057308
• NCBI GeneID: 100302454
• UniProt Accession #: Q9MZR8; Q0MS70
• Molecular Weight: 14.2 kDa
• NCBI Official Full Name: Interleukin-4
• NCBI Official Symbol: IL4
• NCBI Official Synonym Symbols: IL2; BSF-1
• NCBI Protein Information: interleukin-4
• UniProt Protein Name: Interleukin-4
• Protein Family: Interleukin
• UniProt Gene Name: IL4
• UniProt Synonym Gene Names: IL-4; BSF-1

Uniprot Description

Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes. Positively regulates IL31RA expression in macrophages.