Rabbit anti-Human Wingless Type MMTV Integration Site Family, Member 11 (WNT11) Polyclonal Antibody | anti-WNT11 antibody
Biotin-Linked Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11)
NCBI and Uniprot Product Information
NCBI Description
The WNT gene family consists of structurally related genes which encode secreted signaling proteins. These proteins have been implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. This gene is a member of the WNT gene family. It encodes a protein which shows 97%, 85%, and 63% amino acid identity with mouse, chicken, and Xenopus Wnt11 protein, respectively. This gene may play roles in the development of skeleton, kidney and lung, and is considered to be a plausible candidate gene for High Bone Mass Syndrome. [provided by RefSeq, Jul 2008]
Uniprot Description
WNT11: Ligand for members of the frizzled family of seven transmembrane receptors. Probable developmental protein. May be a signaling molecule which affects the development of discrete regions of tissues. Is likely to signal over only few cell diameters. Belongs to the Wnt family.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of Human Ortholog: 11q13.5
Cellular Component: cytoplasm; extracellular region; extracellular space; proteinaceous extracellular matrix
Molecular Function: frizzled binding; GTPase activator activity; protein binding; protein kinase activator activity
Biological Process: activation of protein kinase activity; adrenal gland development; artery morphogenesis; bone mineralization; cell fate commitment; cloacal septation; convergent extension involved in axis elongation; embryonic skeletal system development; epithelial to mesenchymal transition; maintenance of epithelial cell polarity; negative regulation of apoptosis; negative regulation of cell growth; negative regulation of cell migration; negative regulation of transcription, DNA-dependent; neuron differentiation; notochord morphogenesis; osteoblast differentiation; palate development; paraxial mesoderm formation; positive regulation of apoptosis; positive regulation of cell migration; positive regulation of GTPase activity; positive regulation of stress fiber formation; positive regulation of transcription, DNA-templated; positive regulation of transforming growth factor beta2 production; protein amino acid phosphorylation; response to nutrient levels; Wnt receptor signaling pathway through beta-catenin; Wnt receptor signaling pathway, calcium modulating pathway; Wnt receptor signaling pathway, planar cell polarity pathway; Wnt signaling pathway
Research Articles on WNT11
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Product Notes
The WNT11 wnt11 (Catalog #AAA2097051) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Biotin-Linked Polyclonal Antibody to Wingless Type MMTV Integration Site Family, Member 11 (WNT11) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Wingless Type MMTV Integration Site Family, Member 11 (WNT11) can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC). Researchers should empirically determine the suitability of the WNT11 wnt11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Wingless Type MMTV Integration Site Family, Member 11 (WNT11), Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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