SDS-Page
MSRB3 recombinant protein
MSRB3, 21-185aa, Human, His tag, E Coli
Gene Names
MSRB3; DFNB74
Applications
SDS-Page
Purity
> 90% by SDS-PAGE
Synonyms
MSRB3; 21-185aa; Human; His tag; E Coli; Methionine sulfoxide reductase B3; MSRB3 recombinant protein
Host
E Coli
Purity/Purification
> 90% by SDS-PAGE
Form/Format
Liquid. In 20mM Tris-HCl Buffer (pH 8.0) containing 1mM DTT, 10% glycerol, 0.1mM PMSF
Concentration
1 mg/ml (determined by Bradford assay) (varies by lot)
Sequence
MCGLPSGSCR DKKNCKVVFS QQELRKRLTP LQYHVTQEKG TESAFEGEYT HHKDPGIYKC VVCGTPLFKS ETKFDSGSGW PSFHDVINSE AITFTDDFSY GMHRVETSCS QCGAHLGHIF DDGPRPTGKR YCINSAALSF TPADSSGTAE GGSGVASPAQ ADKAELLEHH HHHH
Sequence Length
185
Applicable Applications for MSRB3 recombinant protein
SDS-PAGE
Antigen Species
Human
Tag Information
His-tag
Preparation and Storage
Can be stored at 4 degree C short term (1-2 weeks).
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
For long term storage, aliquot and store at -20 degree C or -70 degree C.
Avoid repeated freezing and thawing cycles.
SDS-Page
SDS-Page
Related Product Information for MSRB3 recombinant protein
Methionine sulfoxide reductase B3, also known as MSRB3, belongs to the methionine sulfoxide reductases (MSR) family proteins. MSRs are thought to protect against reactive oxygen species-induced oxidative damage in many organs, including the most environmentally exposed organ, human skin. MSRB3 plays an important role in cold tolerance by eliminating MetO and ROS that accumulate at the ER during cold acclimation. Recombinant human MSRB3 protein, fused to His-tag at C-terminus, was expressed in E Coli and purified by using conventional chromatography techniques.
Product Categories/Family for MSRB3 recombinant protein
References
Taunqiaruwinai WM., et al. (2009) Am J Dermatopathol. 31 (5):427-31-7.; Kwon SJ., et al. (2007) Plant Cell Physiol. 48 (12):1713-23.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
19 kDa (174aa) confirmed by MALDI-TOF
NCBI Official Full Name
methionine-R-sulfoxide reductase B3 isoform 2
NCBI Official Synonym Full Names
methionine sulfoxide reductase B3
NCBI Official Symbol
MSRB3
NCBI Official Synonym Symbols
DFNB74
NCBI Protein Information
methionine-R-sulfoxide reductase B3
UniProt Protein Name
Methionine-R-sulfoxide reductase B3
Protein Family
UniProt Gene Name
MSRB3
UniProt Synonym Gene Names
MsrB3
NCBI Description
The protein encoded by this gene catalyzes the reduction of methionine sulfoxide to methionine. This enzyme acts as a monomer and requires zinc as a cofactor. Several transcript variants encoding two different isoforms have been found for this gene. One of the isoforms localizes to mitochondria while the other localizes to endoplasmic reticula. [provided by RefSeq, Jul 2010]
Uniprot Description
Catalyzes the reduction of free and protein-bound methionine sulfoxide to methionine. Isoform 2 is essential for hearing.
Research Articles on MSRB3
Similar Products
Product Notes
The MSRB3 msrb3 (Catalog #AAA203811) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The tag for this protein is His-tag. AAA Biotech's MSRB3 can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE. Researchers should empirically determine the suitability of the MSRB3 msrb3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: MCGLPSGSCR DKKNCKVVFS QQELRKRLTP LQYHVTQEKG TESAFEGEYT HHKDPGIYKC VVCGTPLFKS ETKFDSGSGW PSFHDVINSE AITFTDDFSY GMHRVETSCS QCGAHLGHIF DDGPRPTGKR YCINSAALSF TPADSSGTAE GGSGVASPAQ ADKAELLEHH HHHH. It is sometimes possible for the material contained within the vial of "MSRB3, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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