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Sequence Information

Bone Morphogenetic Protein 6 (BMP6) Recombinant Protein | BMP6 recombinant protein

Recombinant Bone Morphogenetic Protein 6 (BMP6)

Gene Names
Bmp6; VGR
Applications
SDS-Page, Western Blot, ELISA, Immunoprecipitation
Purity
> 95%
Synonyms
Bone Morphogenetic Protein 6 (BMP6); Recombinant Bone Morphogenetic Protein 6 (BMP6); BMP6 recombinant protein
Ordering
For Research Use Only!
Host
E Coli
Purity/Purification
> 95%
Form/Format
Supplied as lyophilized form in PBS,pH7.4, containing 5% sucrose, 0.01% sarcosyl.
Sequence
The target protein is fused with N-terminal His-Tag, its sequence is listed below.
MGHHHHHHSGSEF-QQSRNR STQSQDVSRG SSASDYNSSE LKTACKKHEL YVSFQDLGWQ DWIIAPKGYA ANYCDGECSF PLNAHMNATN HAIVQTLVHL MNPEYVPKPC CAPTKLNAIS VLYFDDNSNV ILKKYRNMVV RA
Sequence Length
506
Applicable Applications for BMP6 recombinant protein
SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP)
Organism
Rattus norvegicus (Rat)
Expression System
Prokaryotic expression
Residues
Gln375~Ala502 (Accession # Q04906) with N-terminal His-Tag
Endotoxin Level
<1.0EU per 1ug (determined by the LAL method)
Reconstitution
Reconstitute in sterile PBS, pH7.2-pH7.4.
Preparation and Storage
Avoid repeated freeze/thaw cycles. Store at 2-8 degree C for one month. Aliquot and store at -80 degree C for 12 months.
Stability Test: The thermal stability is described by the loss rate of the targetprotein. The loss rate was determined by accelerated thermal degradation test,that is, incubate the protein at 37 degree C for 48h, and no obvious degradation andprecipitation were observed. (Referring from China Biological Products Standard,which was calculated by the Arrhenius equation.) The loss of this protein is lessthan 5% within the expiration date under appropriate storage condition.

Sequence Information

Sequence Information

SDS-Page

SDS-Page

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
15.9kDa
NCBI Official Full Name
bone morphogenetic protein 6
NCBI Official Synonym Full Names
bone morphogenetic protein 6
NCBI Official Symbol
Bmp6
NCBI Official Synonym Symbols
VGR
NCBI Protein Information
bone morphogenetic protein 6; BMP-6; VGR-1; VG-1-related protein
UniProt Protein Name
Bone morphogenetic protein 6
UniProt Gene Name
Bmp6
UniProt Synonym Gene Names
Bmp-6; Vgr; BMP-6; VGR-1
UniProt Entry Name
BMP6_RAT

NCBI Description

plays a role in induction of osteogenesis; may be involved in liver growth and differentiation in response to injury [RGD, Feb 2006]

Uniprot Description

BMP6: Induces cartilage and bone formation. Belongs to the TGF-beta family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular space; cell; cytoplasm

Molecular Function: growth factor activity; protein heterodimerization activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: cellular iron ion homeostasis; response to glucocorticoid stimulus; regulation of apoptosis; BMP signaling pathway; response to magnesium ion; positive regulation of endothelial cell differentiation; positive regulation of aldosterone biosynthetic process; regulation of cell differentiation; male genitalia development; cell differentiation; kidney development; inflammatory response; response to iron ion; endochondral ossification; ossification; response to retinoic acid; positive regulation of bone mineralization; osteoblast differentiation; positive regulation of osteoblast differentiation; positive regulation of chondrocyte differentiation; eye development; regulation of MAPKKK cascade; cartilage development; immune response; positive regulation of endothelial cell proliferation; positive regulation of transcription from RNA polymerase II promoter; response to activity; positive regulation of neuron differentiation; cell development; positive regulation of epithelial cell proliferation; growth

Research Articles on BMP6

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Product Notes

The BMP6 bmp6 (Catalog #AAA2010601) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. AAA Biotech's Bone Morphogenetic Protein 6 (BMP6) can be used in a range of immunoassay formats including, but not limited to, SDS-PAGE, Western Blot (WB), ELISA (EIA), Immunoprecipitation (IP). Researchers should empirically determine the suitability of the BMP6 bmp6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. The amino acid sequence is listed below: The target protein is fused with N-terminal His-Tag, its sequence is listed below. MGHHHHHHSG SEF-QQSRNR STQSQDVSRG SSASDYNSSE LKTACKKHEL YVSFQDLGWQ DWIIAPKGYA ANYCDGECSF PLNAHMNATN HAIVQTLVHL MNPEYVPKPC CAPTKLNAIS VLYFDDNSNV ILKKYRNMVV RA. It is sometimes possible for the material contained within the vial of "Bone Morphogenetic Protein 6 (BMP6), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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