Typical Testing Data/Standard Curve (for reference only)
(Human IL-17C PicoKine ELISA Kit standard curve )
Human IL-17C ELISA Kit | IL17C elisa kit
Human IL-17C PicoKine ELISA Kit
Gene Names
IL17C; CX2; IL-17C
Reactivity
Human
Synonyms
IL-17C; Human IL-17C PicoKine ELISA Kit; Interleukin-17C; interleukin 17C; CX2; Cytokine CX2; IL 17C; IL 21; IL17C; IL17C_HUMAN; Interleukin 17C; MGC126884; MGC138401; IL17C elisa kit
Reactivity
Human
Specificity
Natural and recombinant human IL-17C
Sequence Length
197
Samples
Cell culture supernates, serum and plasma (heparin, EDTA)
Assay Type
Sandwich
Detection Range
125pg/ml-8000pg/ml
Sensitivity
< 10pg/ml
Intra-assay Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-assay Precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Preparation and Storage
Store at 4 degree C for 6 months, at -20 degree C for 12 months. Avoid multiple freeze-thaw cycles (Shipped with wet ice.)
Typical Testing Data/Standard Curve (for reference only)
(Human IL-17C PicoKine ELISA Kit standard curve )
Typical Testing Data/Standard Curve (for reference only)
(Human IL-17C PicoKine ELISA Kit standard curve )
Related Product Information for IL17C elisa kit
Principle of the assay: human IL-17C ELISA Kit was based on standard sandwich enzyme-linked immune-sorbent assay technology. A monoclonal antibody from mouse specific for IL-17C has been precoated onto 96-well plates. Standards(E.coli, H19-V197) and test samples are added to the wells, a biotinylated detection polyclonal antibody from goat specific for IL-17C is added subsequently and then followed by washing with PBS or TBS buffer. Avidin-Biotin-Peroxidase Complex was added and unbound conjugates were washed away with PBS or TBS buffer. HRP substrate TMB was used to visualize HRP enzymatic reaction. TMB was catalyzed by HRP to produce a blue color product that changed into yellow after adding acidic stop solution. The density of yellow is proportional to the human IL-17C amount of sample captured in plate.
Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.
Background: IL17C, also known as CX2, is a protein that in humans is encoded by the IL17C gene. IL17C is mapped to 16q24.3. The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. IL17C is an essential autocrine cytokine regulating innate epithelial immune responses. It also plays an important role in the pathogenesis of inflammatory arthritis.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
Molecular Weight
21,765 Da
NCBI Official Full Name
Interleukin-17C
NCBI Official Synonym Full Names
interleukin 17C
NCBI Official Symbol
IL17C
NCBI Official Synonym Symbols
CX2; IL-17C
NCBI Protein Information
interleukin-17C; cytokine CX2
UniProt Protein Name
Interleukin-17C
Protein Family
UniProt Gene Name
IL17C
UniProt Synonym Gene Names
IL-17C
UniProt Entry Name
IL17C_HUMAN
NCBI Description
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq, Jul 2008]
Uniprot Description
IL17C: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Belongs to the IL-17 family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 16q24
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; neutrophil differentiation; inflammatory response
Research Articles on IL17C
Similar Products
Product Notes
The Human IL17C il17c (Catalog #AAA177124) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA177124 ELISA Kit recognizes Human IL17C. It is sometimes possible for the material contained within the vial of "IL-17C, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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