Testing Data
(Tramp-C1 cells were stained with MBS600337 or isotype control (open histogram) followed by PE-conjugated anti-rat antibody.)
Rat anti-Mouse Interleukin 17C Monoclonal Antibody | anti-IL17C antibody
Interleukin 17C (IL-17C)
Gene Names
IL17C; CX2; IL-21; IL-17C; MGC126884; MGC138401
Reactivity
Mouse
Applications
ELISA, Flow Cytometry, Functional Assay
Purity
PurifiedPurified by Protein G affinity chromatography.
Synonyms
Interleukin 17C; Monoclonal Antibody; Interleukin 17C (IL-17C); Anti -Interleukin 17C (IL-17C); anti-IL17C antibody
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Isotype
IgG2a
Clone Number
8B28
Specificity
Recognizes mouse Interleukin 17C (IL-17C).
Purity/Purification
Purified
Purified by Protein G affinity chromatography.
Purified by Protein G affinity chromatography.
Form/Format
Supplied as a lyophilized powder from PBS, 5% trehalose. Reconstitute with 200ul sterile PBS.
Applicable Applications for anti-IL17C antibody
ELISA (EL/EIA), Flow Cytometry (FC/FACS)
Application Notes
Suitable for use in ELISA and Flow Cytometry.
Dilution: Flow Cytometry: 25ug/ml; 10ul labels 1-5x10e5 Tramp-C1 cells in a total reaction volume < 200ul. For intracellular staining to detect IL-17C, cells must first be fixed and permeabilized using 4% paraformaldehyde, 0.1% saponin in PBS. The binding of unlabeled monoclonal antibodies may be visualized by adding a secondary developing reagent such as anti-rat IgG (FITC).
Dilution: Flow Cytometry: 25ug/ml; 10ul labels 1-5x10e5 Tramp-C1 cells in a total reaction volume < 200ul. For intracellular staining to detect IL-17C, cells must first be fixed and permeabilized using 4% paraformaldehyde, 0.1% saponin in PBS. The binding of unlabeled monoclonal antibodies may be visualized by adding a secondary developing reagent such as anti-rat IgG (FITC).
Immunogen
Recombinant corresponding to aa15-194 of mouse IL-17C expressed in E. coli.
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Testing Data
(Tramp-C1 cells were stained with MBS600337 or isotype control (open histogram) followed by PE-conjugated anti-rat antibody.)
Testing Data
(Tramp-C1 cells were stained with MBS600337 or isotype control (open histogram) followed by PE-conjugated anti-rat antibody.)
Related Product Information for anti-IL17C antibody
Interleukin 17C (IL-17C) is a disulfide-linked dimer belonging to the IL-17 family. IL-17 family proteins are pro-inflammatory cytokines that induce local cytokine production and are involved in the regulation of immune functions.
Product Categories/Family for anti-IL17C antibody
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
21,765 Da
NCBI Official Full Name
interleukin-17C
NCBI Official Synonym Full Names
interleukin 17C
NCBI Official Symbol
IL17C
NCBI Official Synonym Symbols
CX2; IL-21; IL-17C; MGC126884; MGC138401
NCBI Protein Information
interleukin-17C; cytokine CX2
UniProt Protein Name
Interleukin-17C
Protein Family
UniProt Gene Name
IL17C
UniProt Entry Name
IL17C_HUMAN
NCBI Description
The protein encoded by this gene is a T cell-derived cytokine that shares the sequence similarity with IL17. This cytokine was reported to stimulate the release of tumor necrosis factor alpha and interleukin 1 beta from a monocytic cell line. The expression of this cytokine was found to be restricted to activated T cells. [provided by RefSeq]
Uniprot Description
IL17C: Stimulates the release of tumor necrosis factor alpha and IL-1-beta from the monocytic cell line THP-1. Belongs to the IL-17 family.
Protein type: Secreted; Secreted, signal peptide; Cytokine
Chromosomal Location of Human Ortholog: 16q24
Cellular Component: extracellular space
Molecular Function: cytokine activity
Biological Process: cell surface receptor linked signal transduction; cell-cell signaling; neutrophil differentiation; inflammatory response
Research Articles on IL17C
1. Observational study of gene-disease association and gene-environment interaction. (HuGE Navigator)
Similar Products
Product Notes
The IL17C il17c (Catalog #AAA600337) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Interleukin 17C (IL-17C) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's Interleukin 17C can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Flow Cytometry (FC/FACS). Suitable for use in ELISA and Flow Cytometry. Dilution: Flow Cytometry: 25ug/ml; 10ul labels 1-5x10e5 Tramp-C1 cells in a total reaction volume < 200ul. For intracellular staining to detect IL-17C, cells must first be fixed and permeabilized using 4% paraformaldehyde, 0.1% saponin in PBS. The binding of unlabeled monoclonal antibodies may be visualized by adding a secondary developing reagent such as anti-rat IgG (FITC). Researchers should empirically determine the suitability of the IL17C il17c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Interleukin 17C, Monoclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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