Human Protein argonaute-2, EIF2C2 ELISA Kit | EIF2C2 elisa kit
Human Protein argonaute-2, EIF2C2 ELISA Kit
NCBI and Uniprot Product Information
Uniprot Description
AGO2: the endonuclease in RNA-induced silencing complexes (RISC) that cleaves siRNA/mRNA heteroduplexes bound to RISC. Ago2, along with Dicer and TRBP, are major components of RISC. Interacts with Dicer1 through its Piwi domain. Required for proper fibroblast growth factor signaling during gastrulation. Essential for embryonic development as well as RNA-mediated gene silencing (RNAi).
Protein type: EC 3.1.26.n2; RNA processing; RNA-binding
Cellular Component: cytoplasm; cytosol; dendrite; membrane; mitochondrion; mRNA cap complex; nucleus; polysome; ribonucleoprotein complex
Molecular Function: double-stranded RNA binding; endonuclease activity; endoribonuclease activity; hydrolase activity; metal ion binding; miRNA binding; mRNA binding; nuclease activity; nucleic acid binding; protein binding; protein C-terminus binding; RNA 7-methylguanosine cap binding; RNA binding; single-stranded RNA binding; siRNA binding
Biological Process: cell differentiation; miRNA-mediated gene silencing, miRNA loading onto RISC; miRNA-mediated gene silencing, mRNA cleavage; miRNA-mediated gene silencing, negative regulation of translation; miRNA-mediated gene silencing, production of miRNAs; multicellular organismal development; negative regulation of translational initiation; positive regulation of transcription from RNA polymerase II promoter; post-embryonic development; pre-microRNA processing; regulation of transcription, DNA-dependent; regulation of translation; RNA interference, siRNA loading onto RISC; RNA secondary structure unwinding; RNA-mediated gene silencing; transcription, DNA-dependent
Research Articles on EIF2C2
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Product Notes
The Human EIF2C2 ago2 (Catalog #AAA1606820) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1606820 ELISA Kit recognizes Human EIF2C2. It is sometimes possible for the material contained within the vial of "Protein argonaute-2, EIF2C2, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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