Western Blot (WB)
(RAB39B Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB39B antibody detected the RAB39B protein (arrow).)
Rabbit RAB39B Polyclonal Antibody | anti-RAB39B antibody
RAB39B Antibody (N-term)
Western Blot (WB)
(RAB39B Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB39B antibody detected the RAB39B protein (arrow).)
Western Blot (WB)
(RAB39B Antibody (N-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the RAB39B antibody detected the RAB39B protein (arrow).)
Rab proteins are small GTPases that are involved in vesicular
trafficking.
Ross, M.T., et al. Nature 434(7031):325-337(2005)
Cheng, H., et al. Cytogenet. Genome Res. 97 (1-2), 72-75 (2002) :
Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the Rab family of proteins. Rab proteins are small GTPases that are involved in vesicular trafficking. Mutations in this gene are associated with X-linked mental retardation. [provided by RefSeq, Aug 2013]
Uniprot Description
RAB39B: May be involved in vesicular trafficking. Plays a role in synapse formation. Defects in RAB39B are the cause of mental retardation X- linked type 72 (MRX72). Mental retardation is characterized by significantly below average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period. MRX72 patients can manifest autism spectrum disorder, seizures and macrocephaly as additional features. Belongs to the small GTPase superfamily. Rab family.
Protein type: G protein, monomeric, Rab; G protein, monomeric; G protein
Chromosomal Location of Human Ortholog: Xq28
Cellular Component: Golgi apparatus; neuron projection; plasma membrane; intracellular; vesicle
Molecular Function: GTPase activity; protein binding; GDP binding; GTP binding; myosin V binding
Biological Process: vesicle-mediated transport; intracellular protein transport; metabolic process; synapse organization and biogenesis; Rab protein signal transduction
Disease: Mental Retardation, X-linked 72
Research Articles on RAB39B
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Product Notes
The RAB39B rab39b (Catalog #AAA9209395) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 12-40. The RAB39B Antibody (N-term) reacts with Human, mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's RAB39B can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the RAB39B rab39b for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "RAB39B, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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