Western Blot (WB)
(EIF2C2 Antibody (N-term Q41) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF2C2 antibody detected the EIF2C2 protein (arrow).)
Rabbit EIF2C2 Polyclonal Antibody | anti-Ago2 antibody
EIF2C2 Antibody (N-term)
Western Blot (WB)
(EIF2C2 Antibody (N-term Q41) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF2C2 antibody detected the EIF2C2 protein (arrow).)
Western Blot (WB)
(EIF2C2 Antibody (N-term Q41) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the EIF2C2 antibody detected the EIF2C2 protein (arrow).)
Immunohistochemistry (IHC)
(EIF2C2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2C2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Immunohistochemistry (IHC)
(EIF2C2 Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human stomach tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of EIF2C2 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.)
Flow Cytometry (FC/FACS)
(EIF2C2 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Flow Cytometry (FC/FACS)
(EIF2C2 Antibody (N-term) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.)
Liu, J., et al., Science 305(5689):1437-1441 (2004).
Nelson, P.T., et al., RNA 10(3):387-394 (2004).
Sasaki, T., et al., Genomics 82(3):323-330 (2003).
Doi, N., et al., Curr. Biol. 13(1):41-46 (2003).
NCBI and Uniprot Product Information
Uniprot Description
AGO2: the endonuclease in RNA-induced silencing complexes (RISC) that cleaves siRNA/mRNA heteroduplexes bound to RISC. Ago2, along with Dicer and TRBP, are major components of RISC. Interacts with Dicer1 through its Piwi domain. Required for proper fibroblast growth factor signaling during gastrulation. Essential for embryonic development as well as RNA-mediated gene silencing (RNAi).
Protein type: RNA processing; EC 3.1.26.n2; RNA-binding
Cellular Component: polysome; mRNA cap complex; membrane; cytoplasm; dendrite; cytosol; nucleus; ribonucleoprotein complex
Molecular Function: mRNA binding; endoribonuclease activity; protein binding; siRNA binding; nuclease activity; miRNA binding; nucleic acid binding; hydrolase activity; RNA binding; metal ion binding; endonuclease activity; RNA 7-methylguanosine cap binding
Biological Process: regulation of translation; negative regulation of translational initiation; regulation of transcription, DNA-dependent; transcription, DNA-dependent; pre-microRNA processing; multicellular organismal development; miRNA-mediated gene silencing, mRNA cleavage; miRNA-mediated gene silencing, miRNA loading onto RISC; miRNA-mediated gene silencing, negative regulation of translation; RNA-mediated gene silencing; cell differentiation; post-embryonic development; mRNA cleavage
Research Articles on Ago2
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Product Notes
The Ago2 ago2 (Catalog #AAA9213639) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 27-59. The EIF2C2 Antibody (N-term) reacts with Human (Predicted Reactivity: Bovine, Rabbit, Rat) and may cross-react with other species as described in the data sheet. AAA Biotech's EIF2C2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS). WB~~1:1000. Researchers should empirically determine the suitability of the Ago2 ago2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "EIF2C2, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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