Rabbit anti-Human FABP5 Polyclonal Antibody | anti-FABP5 antibody
FABP5 Antibody
NCBI and Uniprot Product Information
NCBI Description
This gene encodes the fatty acid binding protein found in epidermal cells, and was first identified as being upregulated in psoriasis tissue. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids and other hydrophobic ligands. FABPs may play roles in fatty acid uptake, transport, and metabolism. Polymorphisms in this gene are associated with type 2 diabetes. The human genome contains many pseudogenes similar to this locus.[provided by RefSeq, Feb 2011]
Uniprot Description
FABP5: High specificity for fatty acids. Highest affinity for C18 chain length. Decreasing the chain length or introducing double bonds reduces the affinity. May be involved in keratinocyte differentiation. Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family.
Protein type: Lipid-binding
Chromosomal Location of Human Ortholog: 8q21.13
Cellular Component: cytoplasm; cytosol; nucleoplasm
Molecular Function: fatty acid binding; lipid binding; protein binding; transporter activity
Biological Process: epidermis development; glucose metabolic process; glucose transport; lipid metabolic process; phosphatidylcholine biosynthetic process; triacylglycerol catabolic process