Retinoic Acid Early Transcript 1L Active Protein | RAET1L active protein
Recombinant Human Retinoic Acid Early Transcript 1L
Gene Names
RAET1L; ULBP6
Purity
Greater than 95.0% as determined by SDS-PAGE.
Synonyms
Retinoic Acid Early Transcript 1L; Recombinant Human Retinoic Acid Early Transcript 1L; Retinoic Acid Early Transcript 1L Human Recombinant; early transcript 1L; ULBP6; UL16-binding protein 6; RAET1L; retinoic acid early transcript 1L protein; retinoic acid early transcript 1L; RAET1L Human; RAET1L active protein
Host
Sf9, Baculovirus cells
Purity/Purification
Greater than 95.0% as determined by SDS-PAGE.
Form/Format
The RAET1L solution (1mg/ml) contains 10% glycerol and Phosphate-Buffered Saline (pH7.4).
Sterile filtered colorless solution.
Sterile filtered colorless solution.
Sequence
ADPRRDDPHS LCYDITVIPK FRPGPRWCAV QGQVDEKTFL HYDCGNKTVT PVSPLGKKLN VTMAWKAQNP VLREVVDILT EQLLDIQLEN YTPKEPLTLQ ARMSCEQKAE GHSSGSWQFS IDGQTFLLFD SEKRMWTTVH PGARKMKEKW ENDKDVAMSF HYISMGDCIG WLEDFLMGMD STLEPSAGAP LAMSSGHHHH HH
Biological Activity
Determined by its binding ability in a functional ELISA with Human KLRK1 (CAT# MBS147263).
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks.
Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Store, frozen at -20 degree C for longer periods of time.
For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).
Avoid multiple freeze-thaw cycles.
Related Product Information for RAET1L active protein
Introduction: RAET1L plays a role as a stress-induced ligand for NKG2D receptor. Retinoic Acid Early Transcript 1L (RAET1L) is linked to the cell membrane by the GPI anchor. HCMV infection triggers RAET1L's expression but HCMV alters its function. HCMV-encoded UL16 glycoprotein retains RAET1L/ULBP6 inside the cells, preventing it from reaching the cell surface and being exposed to cells of the immune system. RAET1L has a more restricted expression profile in cell lines and primary human tissues than other NKG2D ligands.
Description: RAET1L Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 202 amino acids (26-218 a.a) and having a molecular mass of 22.9kDa.
RAET1L is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Description: RAET1L Human Recombinant produced in Sf9 Baculovirus cells is a single, glycosylated polypeptide chain containing 202 amino acids (26-218 a.a) and having a molecular mass of 22.9kDa.
RAET1L is fused to a 6 amino acid His-tag at C-terminus & purified by proprietary chromatographic techniques.
Product Categories/Family for RAET1L active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
27,509 Da
NCBI Official Full Name
retinoic acid early transcript 1L protein
NCBI Official Synonym Full Names
retinoic acid early transcript 1L
NCBI Official Symbol
RAET1L
NCBI Official Synonym Symbols
ULBP6
NCBI Protein Information
retinoic acid early transcript 1L protein; UL16 binding protein 6
UniProt Protein Name
Retinoic acid early transcript 1L protein
Protein Family
UniProt Gene Name
RAET1L
UniProt Entry Name
RET1L_HUMAN
NCBI Description
RAET1L belongs to the RAET1 family of major histocompatibility complex (MHC) class I-related genes, which are located within a 180-kb cluster on chromosome 6q24.2-q25.3. The REAT1 genes encode glycoproteins that contain extracellular alpha-1 and alpha-2 domains, but they lack the membrane proximal Ig-like alpha-3 domain. Most RAET1 glycoproteins are anchored to the membrane via glycosylphosphatidylinositol (GPI) linkage (Radosavljevic et al., 2002 [PubMed 11827464]).[supplied by OMIM, Mar 2008]
Uniprot Description
RAET1L: Belongs to the MHC class I family
Protein type: Membrane protein, GPI anchor
Chromosomal Location of Human Ortholog: 6q25.1
Cellular Component: plasma membrane
Molecular Function: peptide antigen binding; natural killer cell lectin-like receptor binding
Biological Process: antigen processing and presentation of peptide antigen via MHC class I; natural killer cell mediated cytotoxicity
Research Articles on RAET1L
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Product Notes
The RAET1L raet1l (Catalog #AAA147419) is an Active Protein produced from Sf9, Baculovirus cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: ADPRRDDPHS LCYDITVIPK FRPGPRWCAV QGQVDEKTFL HYDCGNKTVT PVSPLGKKLN VTMAWKAQNP VLREVVDILT EQLLDIQLEN YTPKEPLTLQ ARMSCEQKAE GHSSGSWQFS IDGQTFLLFD SEKRMWTTVH PGARKMKEKW ENDKDVAMSF HYISMGDCIG WLEDFLMGMD STLEPSAGAP LAMSSGHHHH HH. It is sometimes possible for the material contained within the vial of "Retinoic Acid Early Transcript 1L, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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