Adaptor-Related Protein Complex 1 Associated Regulatory Protein Recombinant Protein | AP1AR recombinant protein
Recombinant Human Adaptor-Related Protein Complex 1 Associated Regulatory Protein
Gene Names
AP1AR; 2C18; GBAR; C4orf16; PRO0971; gamma-BAR
Purity
Greater than 90.0% as determined by SDS-PAGE.
Synonyms
Adaptor-Related Protein Complex 1 Associated Regulatory Protein; Recombinant Human Adaptor-Related Protein Complex 1 Associated Regulatory Protein; AP1AR Human; Adaptor-Related Protein Complex 1 Associated Regulatory Protein Human Recombinant; AP-1 complex-associated regulatory protein; 2c18; Adapter-related protein complex 1-associated regulatory protein; Gamma-1-adaptin brefeldin A resistance protein; GBAR; Gamma-BAR; Gamma-A1-adaptin and kinesin interactor; Gadkin; AP1AR; C4orf16; PRO0971; AP1AR recombinant protein
Host
E Coli
Purity/Purification
Greater than 90.0% as determined by SDS-PAGE.
Form/Format
The AP1AR solution (0.25mg/ml) contains 20mM Tris-HCl buffer (pH 8.0), 0.15M NaCl, 10% glycerol and 1mM DTT.
Sterile Filtered colorless solution.
Sterile Filtered colorless solution.
Sequence
MGSSHHHHHH SSGLVPRGSH MGNCCWTQCF GLLRKEAGRL QRVGGGGGSK YFRTCSRGEH LTIEFENLVE SDEGESPGSS HRPLTEEEIV DLRERHYDSI AEKQKDLDKK IQKELALQEE KLRLEEEALY AAQREAARAA KQRKLLEQER QRIVQQYHPS NNGEYQSSGP EDDFESCLRN MKSQYEVFRS SRLSSDATVL TPNTESSCDL MTKTKSTSGN DDSTSLDLEW EDEEGMNRML PMRERSKTEE DILRAALKYS NKKTGSNPTS ASDDSNGLEW ENDFVSAEMD DNGNSEYSGF VNPVLELSDS GIRHSDTDQQ TR.
Sequence Length
269
Preparation and Storage
Store at 4 degree C if entire vial will be used within 2-4 weeks. Store, frozen at -20 degree C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA).Avoid multiple freeze-thaw cycles.
Related Product Information for AP1AR recombinant protein
Description: AP1AR Human Recombinant produced in E Coli is a single, non-glycosylated polypeptide chain containing 322 amino acids (1-302) and having a molecular mass of 36.4 kDa.AP1AR is fused to a 20 amino acid His-tag at N-terminus & purified by proprietary chromatographic techniques.
Introduction: Adaptor-related protein complex 1 associated regulatory protein (AP1AR) is essential for AP-1 dependent transport between the trans-Golgi network and endosomes. AP1AR regulates the membrane association of AP1G1/Gamma1-adaptin which is one of the subunits of the AP-1 adapter complex. AP1AR plays a role as effector of AP-1 in calcium-induced endo-lysosome secretion. The interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
Introduction: Adaptor-related protein complex 1 associated regulatory protein (AP1AR) is essential for AP-1 dependent transport between the trans-Golgi network and endosomes. AP1AR regulates the membrane association of AP1G1/Gamma1-adaptin which is one of the subunits of the AP-1 adapter complex. AP1AR plays a role as effector of AP-1 in calcium-induced endo-lysosome secretion. The interaction with AP1G1/Gamma1-adaptin attenuates the release of the AP-1 complex from membranes.
Product Categories/Family for AP1AR recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
30,459 Da
NCBI Official Full Name
AP-1 complex-associated regulatory protein isoform b
NCBI Official Synonym Full Names
adaptor-related protein complex 1 associated regulatory protein
NCBI Official Symbol
AP1AR
NCBI Official Synonym Symbols
2C18; GBAR; C4orf16; PRO0971; gamma-BAR
NCBI Protein Information
AP-1 complex-associated regulatory protein; adapter-related protein complex 1-associated regulatory protein; adaptor-related protein complex 1-associated regulatory protein; gadkin; gamma-1-adaptin brefeldin A resistance protein; gamma-A1-adaptin and kinesin interactor; gamma1-adaptin brefeldin A resistance protein, gamma-BAR
UniProt Protein Name
AP-1 complex-associated regulatory protein
Protein Family
UniProt Gene Name
AP1AR
UniProt Synonym Gene Names
C4orf16; GBAR; Gamma-BAR; Gadkin
UniProt Entry Name
AP1AR_HUMAN
Uniprot Description
AP1AR: Necessary for AP-1 dependent transport between the trans-Golgi network and endosomes. Regulates the membrane association of AP1G1/Gamma1-adaptin, one of the subunits of the AP-1 adapter complex. The direct interaction with AP1G1/Gamma1- adaptin attenuates the release of the AP-1 complex from membranes. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Vesicle
Chromosomal Location of Human Ortholog: 4q25
Cellular Component: Golgi apparatus; transport vesicle; late endosome; early endosome
Molecular Function: kinesin binding
Biological Process: protein transport; negative regulation of receptor recycling; vesicle targeting, trans-Golgi to endosome
Research Articles on AP1AR
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Product Notes
The AP1AR ap1ar (Catalog #AAA145704) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: MGSSHHH HHH SSGLVPRGSH MGNCCWTQCF GLLRKEAGRL QRVGGGGGSK YFRTCSRGEH LTIEFENLVE SDEGESPGSS HRPLTEEEIV DLRERHYDSI AEKQKDLDKK IQKELALQEE KLRLEEEALY AAQREAARAA KQRKLLEQER QRIVQQYHPS NNGEYQSSGP EDDFESCLRN MKSQYEVFRS SRLSSDATVL TPNTESSCDL MTKTKSTSGN DDSTSLDLEW EDEEGMNRML PMRERSKTEE DILRAALKYS NKKTGSNPTS ASDDSNGLEW ENDFVSAEMD DNGNSEYSGF VNPVLELSDS GIRHSDTDQQ TR.. It is sometimes possible for the material contained within the vial of "Adaptor-Related Protein Complex 1 Associated Regulatory Protein, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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