Monocyte differentiation antigen CD14 (Cd14) Recombinant Protein | Cd14 recombinant protein
Recombinant Rat Monocyte differentiation antigen CD14 (Cd14)
macrophages. It binds lipopolysaccharide binding protein and recently has been shown to bind apoptotic cells. Alternative splicing results in multiple transcript variants encoding the same isoform.
NCBI and Uniprot Product Information
NCBI Description
component of the lipopolysaccharide receptor complex; mediates LPS-induced neuroinflammation and inflammatory response [RGD, Feb 2006]
Uniprot Description
Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL-) and mediates the cytokine release induced by LDL- ().
Research Articles on Cd14
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Product Notes
The Cd14 cd14 (Catalog #AAA1443444) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 18-342, full length protein. The amino acid sequence is listed below: SPATPEPCEL DQDEESVRCY CNFSDPQPNW SSAFLCAGAE DVEFYGGGRS LEYLLKRVDT EANLGQYTDI IRSLPLKRLT VRSARVPTQI LFGTLRVLGY SGLRELTLEN LEVTGTALSP LLDATGPDLN TLSLRNVSWA TTDTWLAELQ QWLKPGLKVL SIAQAHSLNF SCKQVGVFPA LATLDLSDNP ELGEKGLISA LCPHKFPTLQ VLALRNAGME TTSGVCSALA AARVPLQALD LSHNSLRDTA GTPSCDWPSQ LNSLNLSFTG LEHVPKGLPA KLSVLDLSYN RLDRKPRPEE LPEVGSLSLT GNPFLHSESQ SEAYN. It is sometimes possible for the material contained within the vial of "Monocyte differentiation antigen CD14 (Cd14), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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