Nuclear factor of activated T-cells, cytoplasmic 4 (Nfatc4) Recombinant Protein | Nfatc4 recombinant protein

Recombinant Mouse Nuclear factor of activated T-cells, cytoplasmic 4 (Nfatc4) , partial

• Gene Names: Nfatc4; Nfat3; AW107667; AW546455; 3110041H08Rik
• Purity: Greater or equal to 85% purity as determined by SDS-PAGE.
• Synonyms: Nuclear factor of activated T-cells; cytoplasmic 4 (Nfatc4); Recombinant Mouse Nuclear factor of activated T-cells; partial; Nfatc4 recombinant protein

• Host: E Coli or Yeast or Baculovirus or Mammalian Cell
• Purity/Purification: Greater or equal to 85% purity as determined by SDS-PAGE.
• Form/Format: Lyophilized or liquid (Format to be determined during the manufacturing process)
• Sequence Length: 890

• Species: Mouse
• Preparation and Storage: Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.

Related Product Information for Nfatc4 recombinant protein

The product of this gene is a member of the nuclear factors of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation and an inducible nuclear component. Other members of this family of nuclear factors of activated T cells also participate in the formation of this complex. The product of this gene plays a role in the inducible expression of cytokine genes in T cells, especially in the induction of the IL-2 and IL-4. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene.

NCBI and Uniprot Product Information

• NCBI GI #: 270047510
• NCBI GeneID: 73181
• NCBI Accession #: NP_001161818.1
• NCBI GenBank Nucleotide #: NM_001168346.1
• UniProt Accession #: Q8K120; Q3TXW7; Q9EP91; B5B2X2
• Molecular Weight: 94,459 Da
• NCBI Official Full Name: nuclear factor of activated T-cells, cytoplasmic 4 isoform 2
• NCBI Official Synonym Full Names: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
• NCBI Official Symbol: Nfatc4
• NCBI Official Synonym Symbols: Nfat3; AW107667; AW546455; 3110041H08Rik
• NCBI Protein Information: nuclear factor of activated T-cells, cytoplasmic 4
• UniProt Protein Name: Nuclear factor of activated T-cells, cytoplasmic 4
• Protein Family: Nuclear factor of activated T-cells
• UniProt Gene Name: Nfatc4
• UniProt Synonym Gene Names: NF-AT3

Uniprot Description

Plays a role in the inducible expression of cytokine genes in T-cells, especially in the induction of the IL-2 and IL-4. Transcriptionally repressed by estrogen receptors; this inhibition is further enhanced by estrogen. Increases the transcriptional activity of PPARG and has a direct role in adipocyte differentiation. May play an important role in myotube differentiation (). May play a critical role in cardiac development and hypertrophy. May play a role in deafferentation-induced apoptosis of sensory neurons.