Human zinc finger, MIZ-type containing 1 ELISA Kit | ZMIZ1 elisa kit
Human Zinc finger MIZ domain-containing protein 1, ZMIZ1 ELISA Kit
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the PIAS (protein inhibitor of activated STAT) family of proteins. The encoded protein regulates the activity of various transcription factors, including the androgen receptor, Smad3/4, and p53. The encoded protein may also play a role in sumoylation. A translocation between this locus on chromosome 10 and the protein tyrosine kinase ABL1 locus on chromosome 9 has been associated with acute lymphoblastic leukemia. [provided by RefSeq, Mar 2010]
Uniprot Description
RAI17: Increases ligand-dependent transcriptional activity of AR and promotes AR sumoylation. The stimulation of AR activity is dependent upon sumoylation. 2 isoforms of the human protein are produced by alternative splicing.
Protein type: Transcription, coactivator/corepressor; Nuclear receptor co-regulator
Chromosomal Location of Human Ortholog: 10q22.3
Cellular Component: nucleoplasm; intracellular membrane-bound organelle; cytoplasm; nuclear speck
Molecular Function: zinc ion binding
Biological Process: heart morphogenesis; developmental growth; positive regulation of fibroblast proliferation; transcription, DNA-dependent; in utero embryonic development; vitellogenesis; artery morphogenesis; cell aging; positive regulation of transcription from RNA polymerase II promoter; vasculogenesis
Research Articles on ZMIZ1
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Product Notes
The Human ZMIZ1 zmiz1 (Catalog #AAA9325710) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA9325710 ELISA Kit recognizes Human ZMIZ1. It is sometimes possible for the material contained within the vial of "zinc finger, MIZ-type containing 1, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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