Isocitrate Dehydrogenase-1 Active Protein | IDH1 active protein
Recombinant Yeast Isocitrate Dehydrogenase-1
Gene Names
ICDH; F20D21.16; F20D21_16; ICDH; isocitrate dehydrogenase
Purity
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Synonyms
Isocitrate Dehydrogenase-1; Recombinant Yeast Isocitrate Dehydrogenase-1; IDH1; Isocitrate Dehydrogenase-1 Yeast Recombinant; Isocitrate dehydrogenase [NADP] cytoplasmic; EC 1.1.1.42; Cytosolic NADP-isocitrate dehydrogenase; Oxalosuccinate decarboxylase; IDH; NADP(+)-specific ICDH; IDP; PICD; IDH1 active protein
Host
Yeast cells
Purity/Purification
Greater than 95.0% as determined by: (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE.
Form/Format
One ml of solution contains 0.075 mol/l KPO4, 50% Glycerol, pH 7.1.
Sterile Filtered clear solution.
Sterile Filtered clear solution.
Sequence Length
416
Unit Defenition
One unit is defined as 1 umol of NAD+ production per minute under the assay conditions (25 degree C, pH 7.5).
Biological Activity
The specific activity was found to be 115 U/mg.
Related Product Information for IDH1 active protein
Description: Recombinant Saccharomyces Cerevisiae ICDH (NADP) derived from yeast host cells by using over-expression system, is full length same as designated ICD1 from Saccharomyces Cerevisiae. The N-terminal amino acid Phenylalanine residue next to Met is substituted with Alanine for overexpression. The ICDH is purified by proprietary chromatographic techniques.
Introduction: Isocitrate Dehydrogenase is an enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle.
Introduction: Isocitrate Dehydrogenase is an enzyme of the oxidoreductase class that catalyzes the conversion of isocitrate and NAD+ to yield 2-ketoglutarate, carbon dioxide, and NADH. It occurs in cell mitochondria. The enzyme requires Mg2+, Mn2+; it is activated by ADP, citrate, and Ca2+, and inhibited by NADH, NADPH, and ATP. The reaction is the key rate-limiting step of the citric acid (tricarboxylic) cycle.
Product Categories/Family for IDH1 active protein
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
47,234 Da
NCBI Official Full Name
isocitrate dehydrogenase
NCBI Official Symbol
ICDH
NCBI Official Synonym Symbols
F20D21.16; F20D21_16; ICDH; isocitrate dehydrogenase
NCBI Protein Information
isocitrate dehydrogenase
UniProt Protein Name
Peroxisomal isocitrate dehydrogenase [NADP]
Protein Family
UniProt Gene Name
ICDH
UniProt Entry Name
ICDHX_ARATH
NCBI Description
NADP-specific isocitrate dehydrogenase (ICDH)
Uniprot Description
May be involved in response to oxidative stresses.
Research Articles on IDH1
Similar Products
Product Notes
The IDH1 icdh (Catalog #AAA142430) is an Active Protein produced from Yeast cells and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "Isocitrate Dehydrogenase-1, Active Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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