WAS protein family homolog 1 (wash) Recombinant Protein | wash recombinant protein
Recombinant Drosophila melanogaster WAS protein family homolog 1 (wash)
Gene Names
wash; CG13176; DmelCG13176; p63; p65; Wash; WASH
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
WAS protein family homolog 1 (wash); Recombinant Drosophila melanogaster WAS protein family homolog 1 (wash); wash recombinant protein
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-499, Full length protein
Sequence
MEESPYLHSPYQVAIIATDLHHEDTIIQAAQSLDCLHKTINSIFERIDARLARNGSKVEDINNRVKRAQAKIDALVGSKRAIQIFAPARFPASDVLAPLPATFPQVAANPLMEQQVDQLPQGTYSSHSAADQKPDDADIFFHVRGDREQESPLVAERKITNRTAGLGILPAGGVRSVPSLMRFNTNEFAYGEDLNAWKRSLPPQNARRVASQSTQLTGEKQLAPAPHSLAHGTTKLATPAGDLRYNPAALAAPAIDVPLDLPDLPGIANDLQYEPVEEQTPIAPSQQFGDLPELPDLGLEEQDIIVQAIAAQTHIPGPVRRKSVGQCPSPVTAAPPPPPPPPPPPPPPPPAQTSAIPSPPPFPTKGAVKPLSPSLATPLNMPQPPPATEDPRSELMAAIRNAGGVHGGRLRSPAAAPLDVVDNSRSKAGGAVTGDLMADLHNKLMLRRKGISGSQNPVEATAGNPLMQQLSRVIPPPVQPRKGSKSSDEHSEDDEDGWN
Sequence Length
499
Species
Drosophila melanogaster (Fruit fly)
Preparation and Storage
Store at -20 degrees C. For long-term storage, store at -20 degrees C or -80 degrees C. Store working aliquots at 4 degrees C for up to one week. Repeated freezing and thawing is not recommended.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
53,210 Da
NCBI Official Full Name
washout, isoform B
NCBI Official Synonym Full Names
washout
NCBI Official Symbol
wash
NCBI Official Synonym Symbols
CG13176; DmelCG13176; p63; p65; Wash; WASH
NCBI Protein Information
CG13176 gene product from transcript CG13176-RB
UniProt Protein Name
WASH complex subunit 1
UniProt Gene Name
wash
Uniprot Description
Acts as a nucleation-promoting factor by activating the Arp2/3 complex to induce actin polymerization (PubMed:19633175). Participates in both linear- and branched-actin networks (PubMed:19633175). Functions in linear-filament (bundled F-actin) by acting downstream of Rho1 and regulating actin and microtubule organization during oogenesis (PubMed:19633175). Nucleates actin in an Arp2/3-dependent manner and exhibits F-actin and microtubule bundling and cross-linking activity in the egg chamber (PubMed:19633175). During embryogenesis, acts downstream of Rho1 to activate the Arp2/3 complex which is necessary for the developmental migration of tail hemocytes anteriorly along the ventral midline (PubMed:25739458). Its function in hemocyte transmigration is independent of the WASH complex (PubMed:25739458). May play a role in endosomal sorting; its assembly in the WASH complex may regulate its nucleation-promoting factor (NPF) activity.
Research Articles on wash
1. Drosophila WASH has conserved functions in integrin receptor recycling and lysosome neutralization.
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Product Notes
The wash wash (Catalog #AAA1364229) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-499, Full length protein. The amino acid sequence is listed below: MEESPYLHSP YQVAIIATDL HHEDTIIQAA QSLDCLHKTI NSIFERIDAR LARNGSKVED INNRVKRAQA KIDALVGSKR AIQIFAPARF PASDVLAPLP ATFPQVAANP LMEQQVDQLP QGTYSSHSAA DQKPDDADIF FHVRGDREQE SPLVAERKIT NRTAGLGILP AGGVRSVPSL MRFNTNEFAY GEDLNAWKRS LPPQNARRVA SQSTQLTGEK QLAPAPHSLA HGTTKLATPA GDLRYNPAAL AAPAIDVPLD LPDLPGIAND LQYEPVEEQT PIAPSQQFGD LPELPDLGLE EQDIIVQAIA AQTHIPGPVR RKSVGQCPSP VTAAPPPPPP PPPPPPPPPP AQTSAIPSPP PFPTKGAVKP LSPSLATPLN MPQPPPATED PRSELMAAIR NAGGVHGGRL RSPAAAPLDV VDNSRSKAGG AVTGDLMADL HNKLMLRRKG ISGSQNPVEA TAGNPLMQQL SRVIPPPVQP RKGSKSSDEH SEDDEDGWN. It is sometimes possible for the material contained within the vial of "WAS protein family homolog 1 (wash), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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