Vaspin Recombinant Protein
Vaspin, Recombinant, Mouse (Visceral Adipose Tissue-derived Serine Protease Inhibitor, Serpin A12, OL-64)
Purity
Highly Purified>90% (SDS-PAGE)
Synonyms
Vaspin; Recombinant; Mouse (Visceral Adipose Tissue-derived Serine Protease Inhibitor; Serpin A12; OL-64); Vaspin recombinant protein
Host
Mouse, HEK 293 cells
Purity/Purification
Highly Purified
>90% (SDS-PAGE)
>90% (SDS-PAGE)
Form/Format
Supplied as a 0.2um-filtered solution in PBS, pH 7.2.
Sequence
Mouse vaspin (aa 21-413) is fused at the N-terminus to a DYKDDDDK-tag.
Preparation and Storage
Short-term Storage: +4 degree C
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
Long-term Storage: -20 degree C
Working aliquots are stable for up to 3 months when stored at -20 degree C.
Related Product Information for Vaspin recombinant protein
Vaspin (Visceral adipose tissue-derived serpin; Serpin A12), a serine protease inhibitor (serpin), is an insulin-sensitizing adipocytokine that has been isolated from both visceral and subcutaneous white adipose tissue. Based on recent findings, vaspin is suggested to regulate immune responses and inflammation and was found to be correlated with various metabolic parameters. Vaspin may represent a novel biomarker for obesity and impaired insulin sensitivity and might serve as a new therapeutic target of metabolic syndrome.
Product Categories/Family for Vaspin recombinant protein
NCBI and Uniprot Product Information
NCBI GI #
Molecular Weight
~50kD (SDS-PAGE)
NCBI Official Full Name
visceral adipose tissue specific SERPIN
Uniprot Description
SERPINA12: May modulate insulin action conceivably only in the presence of its yet undefined target proteases in white adipose tissues. Belongs to the serpin family.
Protein type: Inhibitor; Secreted; Secreted, signal peptide
Cellular Component: extracellular space; plasma membrane
Molecular Function: serine-type endopeptidase inhibitor activity
Biological Process: positive regulation of phosphoinositide 3-kinase cascade; negative regulation of lipid biosynthetic process; negative regulation of gluconeogenesis; glucose metabolic process; positive regulation of insulin receptor signaling pathway
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Product Notes
The Vaspin (Catalog #AAA637567) is a Recombinant Protein produced from Mouse, HEK 293 cells and is intended for research purposes only. The product is available for immediate purchase. The amino acid sequence is listed below: Mouse vaspin (aa 21-413) is fused at the N-terminus to a DYKDDDDK-t ag. It is sometimes possible for the material contained within the vial of "Vaspin, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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