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T4 UvsX DNA Recombinase Recombinant Protein | T4 recombinant protein
T4 UvsX DNA Recombinase
Gene Names
uvsX; fdsA
Synonyms
T4 UvsX DNA Recombinase; T4 recombinant protein
Host
E Coli
Form/Format
Recombinant protein stored in 50mM sodium phosphate, pH7.5, 300mM NaCl, 20% glycerol, 1mM DTT.
Tag
Tag-free
Species
Escherichia virus T4
Preparation and Storage
Store product at -70 degree C. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
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(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet)
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(Purity: Sample Purity Data. For specific information on a given lot, see related technical data sheet)
Related Product Information for T4 recombinant protein
Recombinant tag-free full-length T4 UvsX DNA Recombinase from Escherichia virus T4 was expressed in E Coli. The gene accession number is P04529.
Homologous recombination is important for error-free repair of DNA double-strand breaks and to restart stalled replication fork. Recombinases of the RecA/RAD51 family perform the central catalytic role in DNA repair and replication. UvsX recombinase is the RecA/Rad51 ortholog of bacteriophage T4. UvsX DNA Recombinase and other recombinases bind to regions of ssDNA to form a presynaptic filament which activates recombination activity to search for homology in dsDNA and to perform DNA strand exchange (1,2)
Homologous recombination is important for error-free repair of DNA double-strand breaks and to restart stalled replication fork. Recombinases of the RecA/RAD51 family perform the central catalytic role in DNA repair and replication. UvsX recombinase is the RecA/Rad51 ortholog of bacteriophage T4. UvsX DNA Recombinase and other recombinases bind to regions of ssDNA to form a presynaptic filament which activates recombination activity to search for homology in dsDNA and to perform DNA strand exchange (1,2)
Product Categories/Family for T4 recombinant protein
References
1. Fujisawa, H. et al: Sequence of the T4 recombination gene, uvsX, and its comparison with that of the recA gene of Escherichia coli. Nucleic acids research, 1985; 13(20): 7473-7481. 2. Maher, R.L. et al: Coordinated binding of single-stranded and double-stranded DNA by UvsX Recombinase. PLoS One. 2013;8(6):e66654.
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
60 kDa
NCBI Official Full Name
UvsX RecA-like recombination protein
NCBI Official Symbol
uvsX
NCBI Official Synonym Symbols
fdsA
NCBI Protein Information
RecA-like recombination protein, DNA-dependent ATPase
UniProt Protein Name
Recombination and repair protein
Protein Family
UniProt Gene Name
UVSX
UniProt Entry Name
UVSX_BPT4
Uniprot Description
Important in genetic recombination, DNA repair, and replication. Possesses pairing and strand-transfer activity. Interacts with dda and gene 32 proteins.
Research Articles on T4
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Product Notes
The T4 uvsx (Catalog #AAA517715) is a Recombinant Protein produced from E Coli and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "T4 UvsX DNA Recombinase, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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