Typical Testing Data/Standard Curve (for reference only)
Rat SUMO-conjugating enzyme UBC9 ELISA Kit | Ube2i elisa kit
Rat SUMO-conjugating enzyme UBC9 ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
NCBI and Uniprot Product Information
NCBI Description
ubuiquitin-conjugating enzyme (E2 class), catalyzes the attachment of ubiquitin-like protein Sumo1 to other proteins; may be involved in the regulation of cell growth and differentiation [RGD, Feb 2006]
Uniprot Description
UBC9: Accepts the ubiquitin-like proteins SUMO1, SUMO2, SUMO3 and SUMO4 from the UBLE1A-UBLE1B E1 complex and catalyzes their covalent attachment to other proteins with the help of an E3 ligase such as RANBP2 or CBX4. Can catalyze the formation of poly- SUMO chains. Necessary for sumoylation of FOXL2 and KAT5. Essential for nuclear architecture and chromosome segregation. Interacts with HIPK1, HIPK2, PPM1J, RASD2 and TCF3 Interacts with NR2C1; the interaction promotes its sumoylation. Forms a tight complex with RANGAP1 and RANBP2. Interacts with SIAH1 and PARP. Interacts with various transcription factors such as TFAP2A, TFAP2B, TFAP2C, AR, ETS1 and SOX4. Interacts with RWDD3; the interaction enhances the sumoylation of a number of proteins such as HIF1A and I-kappa-B. Interacts with DNMT1. Interacts with FOXL2. Forms a complex with SENP6 and UBE2I in response to UV irradiation. Interacts with human herpesvirus 6 IE2. Interacts with human adenovirus early E1A protein; this interaction interferes with polysumoylation (Probable). Interacts with DNM1l (via its GTPase and B domains); the interaction promotes sumoylation of DNM1L, mainly in its B domain. Interacts with PML-RARA oncoprotein (via the coiled-colied domain); the interaction is required for sumoylation of the PML- RARA oncoprotein. Interacts with IPO13. Interacts with NFATC2IP; this inhibits formation of poly-SUMO chains. Expressed in heart, skeletal muscle, pancreas, kidney, liver, lung, placenta and brain. Also expressed in testis and thymus. Belongs to the ubiquitin-conjugating enzyme family.
Protein type: EC 6.3.2.-; Ubiquitin ligase; SUMO conjugating system; Nuclear receptor co-regulator; Ligase; Ubiquitin conjugating system; EC 6.3.2.19
Cellular Component: cytoplasm; dendrite; fibrillar center; nuclear body; nuclear envelope; nucleus; PML body; synapse
Molecular Function: ATP binding; bHLH transcription factor binding; enzyme binding; HLH domain binding; ligase activity; protein binding; protein C-terminus binding; SUMO ligase activity; transcription factor binding; ubiquitin protein ligase binding; ubiquitin-protein ligase activity
Biological Process: cell division; chromosome segregation; mitosis; negative regulation of transcription from RNA polymerase II promoter; negative regulation of transcription, DNA-dependent; positive regulation of I-kappaB kinase/NF-kappaB cascade; positive regulation of steroid hormone receptor signaling pathway; positive regulation of transcription factor activity; proteasomal ubiquitin-dependent protein catabolic process; protein sumoylation; protein ubiquitination; regulation of receptor activity; ubiquitin-dependent protein catabolic process
Research Articles on Ube2i
Similar Products
Product Notes
The Rat Ube2i ube2i (Catalog #AAA2887600) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA2887600 ELISA Kit recognizes Rat Ube2i. It is sometimes possible for the material contained within the vial of "SUMO-conjugating enzyme UBC9, ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
If you are ready to order, navigate to Shopping Cart and get ready to checkout.
