Mouse tumor necrosis factor (ligand) superfamily, member 14 ELISA Kit | TNFSF14 elisa kit

Mouse Tumor necrosis factor ligand superfamily member 14, TNFSF14 ELISA Kit

Cat. Num. AAA945084

• Gene Names: Tnfsf14; LTg; HVEML; LIGHT; Ly113; HVEM-L
• Reactivity: Mouse
• Synonyms: tumor necrosis factor (ligand) superfamily; member 14; Mouse Tumor necrosis factor ligand superfamily member 14; TNFSF14 ELISA Kit; Mouse Tumor necrosis factor ligand superfamily member 14 (TNFSF14) ELISA kit; CD258; HVEML; LIGHT; LTg; TR2; delta transmembrane LIGHT; herpesvirus entry mediator A; ligand for herpesvirus entry mediator; tumor necrosis factor ligand superfamily; tumor necrosis factor; TNFSF14 elisa kit

• Reactivity: Mouse
• Specificity: This assay has high sensitivity and excellent specificity for detection of human TNFAIP6. No significant cross-reactivity or interference between human TNFAIP6 and analogues was observed.
• Sequence Length: 239

• Samples: Serum, Plasma, Cell Culture Supernates
• Assay Type: Quantitative Sandwich
• Detection Range: 0.156 ng/ml-10 ng/ml
• Sensitivity: 0.039 ng/ml.
• Intra-assay Precision: Intra-assay Precision (Precision within an assay): CV%<8%. Three samples of known concentration were tested twenty times on one plate to assess
• Inter-assay Precision: Inter-assay Precision (Precision between assays): CV%<10%. Three samples of known concentration were tested in twenty assays to assess.
• Preparation and Storage: Unopened test kits should be stored at 2 to 8 degree C upon receipt. Please refer to pdf manual for further storage instructions.

Related Product Information for TNFSF14 elisa kit

Principle of the Assay: This assay employs the quantitative sandwich enzyme immunoassay technique. Antibody specific for TNFAIP6 has been pre-coated onto a microplate. Standards and samples are pipetted into the wells and any TNFAIP6 present is bound by the immobilized antibody. After removing any unbound substances, a biotin-conjugated antibody specific for TNFAIP6 is added to the wells. After washing, avidin conjugated Horseradish Peroxidase (HRP) is added to the wells. Following a wash to remove any unbound avidin-enzyme reagent, a substrate solution is added to the wells and color develops in proportion to the amount of TNFAIP6 bound in the initial step. The color development is stopped and the intensity of the color is measured.

NCBI and Uniprot Product Information

• NCBI GI #: 9507195
• NCBI GeneID: 50930
• NCBI Accession #: NP_062291.1
• NCBI GenBank Nucleotide #: NM_019418.3
• UniProt Accession #: Q9QYH9; Q059Y9
• Molecular Weight: 26,338 Da
• NCBI Official Full Name: tumor necrosis factor ligand superfamily member 14
• NCBI Official Synonym Full Names: tumor necrosis factor (ligand) superfamily, member 14
• NCBI Official Symbol: Tnfsf14
• NCBI Official Synonym Symbols: LTg; HVEML; LIGHT; Ly113; HVEM-L
• NCBI Protein Information: tumor necrosis factor ligand superfamily member 14
• UniProt Protein Name: Tumor necrosis factor ligand superfamily member 14
• Protein Family: Tumor necrosis factor ligand superfamily
• UniProt Gene Name: Tnfsf14
• UniProt Synonym Gene Names: Light
• UniProt Entry Name: TNF14_MOUSE

Uniprot Description

TNFSF14: Cytokine that binds to TNFRSF3/LTBR. Binding to the decoy receptor TNFRSF6B modulates its effects. Activates NFKB, stimulates the proliferation of T-cells, and inhibits growth of the adenocarcinoma HT-29. Acts as a receptor for Herpes simplex virus. Belongs to the tumor necrosis factor family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Inhibitor; Cytokine; Membrane protein, integral

Cellular Component: extracellular space; membrane; extracellular region; plasma membrane; integral to membrane

Molecular Function: caspase inhibitor activity; cytokine activity; tumor necrosis factor receptor binding; receptor binding

Biological Process: release of cytoplasmic sequestered NF-kappaB; T cell costimulation; immune response; negative regulation of caspase activity; positive regulation of myoblast differentiation