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SDS-PAGE

TNFR1 / CD120a / TNFRSF1A recombinant protein

Recombinant Rat TNFR1 / CD120a / TNFRSF1A Protein (His tag)

Purity
> 95 % as determined by SDS-PAGE
Synonyms
TNFR1 / CD120a / TNFRSF1A; Recombinant Rat TNFR1 / CD120a / TNFRSF1A Protein (His tag); TNFRSF1A; Tnfr-1; Tnfr1; TNFR1 / CD120a / TNFRSF1A recombinant protein
Ordering
For Research Use Only!
Host
Human Cells
Purity/Purification
> 95 % as determined by SDS-PAGE
Form/Format
Lyophilized from sterile PBS, pH 7.4
Application Notes
The recombinant rat TNFRSF1A comprises 201 amino acids and predicts a molecular mass of 22.3 kDa. The apparent molecular mass of the recombinant protein is approximately 33-38 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Predicted N Terminal
Ile 22
Endotoxin
< 1.0 EU per mug of the protein as determined by the LAL method
Preparation and Storage
Samples are stable for up to twelve months from date of receipt at -70 degree C

SDS-PAGE

SDS-PAGE
Related Product Information for TNFR1 / CD120a / TNFRSF1A recombinant protein
Background: The cluster of differentiation (CD) system is commonly used as cell markers in immunophynotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with the immune function of the cell. There are more than 320 CD unique clusters and subclusters have been identified. Some of the CD molecules serve as receptors or ligands important to the cell through initiating a signal cascade which then alter the behavior of the cell. Some CD proteins do not take part in cell signal process but have other functions such as cell adhesion. CD120a (cluste of differentiation 120a), also known as TNFR1 / TNFRSF1A, is a member of CD family, tumor necrosis factor receptor superfamily. CD120a is one of the most primary receptors for the tumor necrosis factor-alpha. It has been shown to be localized to both plasma membrane lipid rafts and the trans golgi complex with the help of the death domain (DD). CD120a can activate the transcription factor NF-kappaB, mediate apoptosis, and regulate inflammation processes.

Description: A DNA sequence encoding the rat TNFRSF1A (Met1-Ala211) was expressed with a polyhistidine tag at the C-terminus.

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Product Notes

The TNFR1 / CD120a / TNFRSF1A (Catalog #AAA2547441) is a Recombinant Protein produced from Human Cells and is intended for research purposes only. The product is available for immediate purchase. The recombinant rat TNFRSF1A comprises 201 amino acids and predicts a molecular mass of 22.3 kDa. The apparent molecular mass of the recombinant protein is approximately 33-38 kDa in SDS-PAGE under reducing conditions due to glycosylation. Researchers should empirically determine the suitability of the TNFR1 / CD120a / TNFRSF1A for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "TNFR1 / CD120a / TNFRSF1A, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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