Enteropeptidase (Tmprss15), partial Recombinant Protein | Tmprss15 recombinant protein
Recombinant Mouse Enteropeptidase (Tmprss15), partial
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that proteolytically activates the pancreatic proenzyme trypsinogen, converting it into trypsin. The encoded protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2013]
Uniprot Description
PRSS7: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD); a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive. Belongs to the peptidase S1 family.
Protein type: EC 3.4.21.9; Protease; Membrane protein, integral
Cellular Component: membrane; integral to membrane
Molecular Function: peptidase activity; hydrolase activity; serine-type peptidase activity; serine-type endopeptidase activity; catalytic activity; scavenger receptor activity
Biological Process: proteolysis
Research Articles on Tmprss15
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Product Notes
The Tmprss15 tmprss15 (Catalog #AAA1103019) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 830-1069. Partial. The amino acid sequence is listed below: IVGGSDAQAG AWPWVVALYH RDRSTDRLLC GASLVSSDWL VSAAHCVYRR NLDPTRWTAV LGLHMQSNLT SPQVVRRVVD QIVINPHYDR RRKVNDIAMM HLEFKVNYTD YIQPICLPEE NQIFIPGRTC SIAGWGYDKI NAGSTVDVLK EADVPLISNE KCQQQLPEYN ITESMICAGY EEGGIDSCQG DSGGPLMCQE NNRWFLVGVT SFGVQCALPN HPGVYVRVSQ FIEWIHSFLH . It is sometimes possible for the material contained within the vial of "Enteropeptidase (Tmprss15), partial, Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
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