Western Blot (WB)
(Anti-Enteropeptidase Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Rabbit anti-Human Enterokinase/Enteropeptidase Polyclonal Antibody | anti-TMPRSS15 antibody
Enterokinase/Enteropeptidase Antibody (C-term)
Western Blot (WB)
(Anti-Enteropeptidase Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Western Blot (WB)
(Anti-Enteropeptidase Antibody (C-term) at 1:1000 dilution + Jurkat whole cell lysateLysates/proteins at 20 ug per lane. SecondaryGoat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 113 kDaBlocking/Dilution buffer: 5% NFDM/TBST.)
Background: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes an enzyme that converts the pancreatic proenzyme trypsinogen to trypsin, which activates other proenzymes including chymotrypsinogen and procarboxypeptidases. The precursor protein is cleaved into two chains that form a heterodimer linked by a disulfide bond. This protein is a member of the trypsin family of peptidases. Mutations in this gene cause enterokinase deficiency, a malabsorption disorder characterized by diarrhea and failure to thrive. [provided by RefSeq, Jul 2008]
Uniprot Description
PRSS7: Responsible for initiating activation of pancreatic proteolytic proenzymes (trypsin, chymotrypsin and carboxypeptidase A). It catalyzes the conversion of trypsinogen to trypsin which in turn activates other proenzymes including chymotrypsinogen, procarboxypeptidases, and proelastases. Defects in TMPRSS15 are a cause of enterokinase deficiency (ENTKD); a life-threatening intestinal malabsorption disorder characterized by diarrhea and failure to thrive. Belongs to the peptidase S1 family.
Protein type: Protease; Membrane protein, integral; EC 3.4.21.9
Chromosomal Location of Human Ortholog: 21q21.1
Cellular Component: brush border; integral to membrane
Molecular Function: protein binding; scavenger receptor activity; serine-type endopeptidase activity
Biological Process: proteolysis; receptor-mediated endocytosis
Disease: Enterokinase Deficiency
Research Articles on TMPRSS15
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Product Notes
The TMPRSS15 tmprss15 (Catalog #AAA9217079) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Enterokinase/Enteropeptidase Antibody (C-term) reacts with Human and may cross-react with other species as described in the data sheet. AAA Biotech's Enterokinase/Enteropeptidase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB:~~1:1000. Researchers should empirically determine the suitability of the TMPRSS15 tmprss15 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Enterokinase/Enteropeptidase, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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