Transmembrane emp24 domain-containing protein 7 (Tmed7) Recombinant Protein | Tmed7 recombinant protein
Recombinant Rat Transmembrane emp24 domain-containing protein 7 (Tmed7)
NCBI and Uniprot Product Information
NCBI Description
radiation-induced gene [RGD, Feb 2006]
Uniprot Description
Function: Potential role in vesicular protein trafficking, mainly in the early secretory pathway. Appears to play a role in the biosynthesis of secreted cargo including processing and post-translational modifications
By similarity.
Subunit structure: Predominantly monomeric and to lesser extent homodimeric in endoplasmic reticulum, endoplasmic reticulum-Golgi intermediate compartment and trans-Golgi network. Oligomerizes with other members of the EMP24/GP25L family such as TMED2, TMED9 and TMED10. Interacts (via C-terminus) with COPG1; the interaction involves dimeric TMED7
By similarity. Ref.3
Subcellular location: Endoplasmic reticulum membrane; Single-pass type I membrane protein. Golgi apparatus › cis-Golgi network membrane; Single-pass type I membrane protein. Endoplasmic reticulum-Golgi intermediate compartment membrane; Single-pass type I membrane protein. Cytoplasmic vesicle › COPI-coated vesicle membrane; Single-pass type I membrane protein
By similarity. Cytoplasmic vesicle › COPII-coated vesicle membrane; Single-pass type I membrane protein
By similarity. Note: Cycles between compartments of the early secretatory pathway. Ref.3
Post-translational modification: N-linked glycosylated in complex form containing terminal sialic acid
By similarity.
Sequence similarities: Belongs to the EMP24/GP25L family.Contains 1 GOLD domain.
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Product Notes
The Tmed7 tmed7 (Catalog #AAA1134331) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 36-226. The amino acid sequence is listed below: GSEITFELPD NAKQCFYEDI TQGTKCTLEF QVITGGHYDV DCRLEDPDGK VLYKEMKKQY DSFTFTASKN GTYKFCFSNE FSTFTHKTVY FDFQVGEDPP LFPSENRVSA LTQMESACVS IHEALKSVID YQTHFRLREA QGRSRAEDLN TRVAYWSVGE ALILLVVSIG QVFLLKSFFS DKRTTTTRVG S. It is sometimes possible for the material contained within the vial of "Transmembrane emp24 domain-containing protein 7 (Tmed7), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
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