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Western Blot (WB) (Mouse Map2k6 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map2k6 antibody detected the Map2k6 protein (arrow).)

Rabbit Map2k6 Polyclonal Antibody | anti-Map2k6 antibody

Mouse Map2k6 Antibody (N-term)

Gene Names
Map2k6; MEK6; MKK6; Prkmk6; SAPKK3
Reactivity
Mouse (Predicted Reactivity: Bovine)
Applications
Western Blot, ELISA
Purity
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Synonyms
Map2k6; Polyclonal Antibody; Mouse Map2k6 Antibody (N-term); Dual specificity mitogen-activated protein kinase kinase 6; MAP kinase kinase 6; MAPKK 6; MAPK/ERK kinase 6; MEK 6; SAPKK3; Prkmk6; Sapkk3; anti-Map2k6 antibody
Ordering
For Research Use Only!
Host
Rabbit
Reactivity
Mouse (Predicted Reactivity: Bovine)
Clonality
Polyclonal
Isotype
Rabbit Ig
Specificity
This Mouse Map2k6 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30-57 amino acids from the N-terminal region of mouse Map2k6.
Purity/Purification
Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)
Form/Format
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Concentration
Vial Concentration: 0.5 (varies by lot)
Sequence Positions
30-57
Sequence Length
334
Applicable Applications for anti-Map2k6 antibody
Western Blot (WB), ELISA (EIA)
Application Notes
WB~~1:1000
Antigen Type
Synthetic Peptide
Antigen Source
MOUSE
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Western Blot (WB)

(Mouse Map2k6 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map2k6 antibody detected the Map2k6 protein (arrow).)

Western Blot (WB) (Mouse Map2k6 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map2k6 antibody detected the Map2k6 protein (arrow).)
Related Product Information for anti-Map2k6 antibody
Map2k6 catalyzes the concomitant phosphorylation of a threonine and a tyrosine residue in MAP kinase p38 exclusively.
Product Categories/Family for anti-Map2k6 antibody
References
Remy, G., et al. Cell. Signal. 22(4):660-667(2010)
Sorkin, L.S., et al. Neuroscience 162(2):462-471(2009)
Yoshizawa, T., et al. J. Immunol. 183(2):1360-1367(2009)
Bulat, N., et al. J. Lipid Res. 50(1):81-89(2009)
Yamashita, T., et al. Biochem. Biophys. Res. Commun. 365(2):252-257(2008)

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
37432
NCBI Official Full Name
dual specificity mitogen-activated protein kinase kinase 6
NCBI Official Synonym Full Names
mitogen-activated protein kinase kinase 6
NCBI Official Symbol
Map2k6
NCBI Official Synonym Symbols
MEK6; MKK6; Prkmk6; SAPKK3
NCBI Protein Information
dual specificity mitogen-activated protein kinase kinase 6
UniProt Protein Name
Dual specificity mitogen-activated protein kinase kinase 6
UniProt Gene Name
Map2k6
UniProt Synonym Gene Names
Prkmk6; Sapkk3; MAP kinase kinase 6; MAPKK 6; MEK 6
UniProt Entry Name
MP2K6_MOUSE

Uniprot Description

MKK6: a dual-specificity protein kinase of the STE7 family. Activates p38 MAP kinase by phosphorylating a Thr and a Tyr residue in the activation loop. Is activated by cytokines and environmental stress in vivo. Three alternatively spliced isoforms have been reported.

Protein type: Protein kinase, dual-specificity (non-receptor); Protein kinase, STE; Kinase, protein; EC 2.7.12.2; STE group; STE7 family

Cellular Component: cytoskeleton; cytoplasm; intracellular; nucleus

Molecular Function: transferase activity; MAP kinase kinase activity; protein serine/threonine kinase activity; protein binding; protein-tyrosine kinase activity; transferase activity, transferring phosphorus-containing groups; nucleotide binding; kinase activity; protein kinase binding; ATP binding; protein kinase activity; receptor signaling protein serine/threonine kinase activity

Biological Process: transcription, DNA-dependent; apoptosis; activation of MAPK activity; positive regulation of apoptosis; MAPKKK cascade; protein amino acid phosphorylation; regulation of transcription, DNA-dependent; positive regulation of prostaglandin secretion; response to stress; positive regulation of protein amino acid phosphorylation; phosphorylation; cardiac muscle contraction; positive regulation of nitric-oxide synthase biosynthetic process

Research Articles on Map2k6

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Product Notes

The Map2k6 map2k6 (Catalog #AAA9213554) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 30-57. The Mouse Map2k6 Antibody (N-term) reacts with Mouse (Predicted Reactivity: Bovine) and may cross-react with other species as described in the data sheet. AAA Biotech's Map2k6 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), ELISA (EIA). WB~~1:1000. Researchers should empirically determine the suitability of the Map2k6 map2k6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "Map2k6, Polyclonal Antibody" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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