Human TATA box binding protein (TBP) -associated factor, RNA polymerase I, D, 41kDa ELISA Kit | TAF1D elisa kit

Human TATA box-binding protein-associated factor RNA polymerase I subunit D, TAF1D ELISA Kit

Cat. Num. AAA9319784

• Gene Names: TAF1D; JOSD3; RAFI41; TAFI41; TAF(I)41
• Reactivity: Human
• Synonyms: TATA box binding protein (TBP) -associated factor; RNA polymerase I; D; 41kDa; Human TATA box-binding protein-associated factor RNA polymerase I subunit D; TAF1D ELISA Kit; Human TATA box-binding protein-associated factor RNA polymerase I subunit D (TAF1D) ELISA kit; JOSD3; MGC5306; RAFI41; TAF (I) 41; Josephin domain containing 3; TAF1D elisa kit

• Reactivity: Human

• Preparation and Storage: Store all reagents at 2-8 degree C

NCBI and Uniprot Product Information

• NCBI GI #: 13129136
• NCBI GeneID: 79101
• NCBI Accession #: NP_077021.1
• NCBI GenBank Nucleotide #: NM_024116.3
• UniProt Accession #: Q9H5J8; Q6I9Y6
• Molecular Weight: 32,058 Da
• NCBI Official Full Name: TATA box-binding protein-associated factor RNA polymerase I subunit D
• NCBI Official Synonym Full Names: TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa
• NCBI Official Symbol: TAF1D
• NCBI Official Synonym Symbols: JOSD3; RAFI41; TAFI41; TAF(I)41
• NCBI Protein Information: TATA box-binding protein-associated factor RNA polymerase I subunit D; TBP-associated factor 1D; Josephin domain containing 3; TATA box-binding protein-associated factor 1D; transcription initiation factor SL1/TIF-IB subunit D; RNA polymerase I-specific TBP-associated factor 41 kDa
• UniProt Protein Name: TATA box-binding protein-associated factor RNA polymerase I subunit D
• Protein Family: TATA box-binding protein-associated factor
• UniProt Gene Name: TAF1D
• UniProt Synonym Gene Names: JOSD3; TAFI41; TBP-associated factor 1D
• UniProt Entry Name: TAF1D_HUMAN

NCBI Description

TAF1D is a member of the SL1 complex, which includes TBP (MIM 600075) and TAF1A (MIM 604903), TAF1B (MIM 604904), and TAF1C (MIM 604905), and plays a role in RNA polymerase I transcription (Wang et al., 2004 [PubMed 15520167]; Gorski et al., 2007 [PubMed 17318177]).[supplied by OMIM, Jun 2009]

Uniprot Description

TAF1D: Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.

Chromosomal Location of Human Ortholog: 11q21

Cellular Component: nucleoplasm; microtubule organizing center

Molecular Function: protein binding; DNA binding

Biological Process: chromatin silencing at rDNA; negative regulation of gene expression, epigenetic; transcription from RNA polymerase I promoter; RNA elongation from RNA polymerase I promoter; gene expression; termination of RNA polymerase I transcription; transcription initiation from RNA polymerase I promoter; regulation of gene expression, epigenetic