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SDS-PAGE

Protachykinin-1 (TAC1) Recombinant Protein | TAC1 recombinant protein

Recombinant Human Protachykinin-1 (TAC1)

Gene Names
TAC1; NK2; NPK; NKNA; TAC2; Hs.2563
Purity
Greater or equal to 85% purity as determined by SDS-PAGE.
Synonyms
Protachykinin-1 (TAC1); Recombinant Human Protachykinin-1 (TAC1); Recombinant Protachykinin-1 (TAC1); Protachykinin-1; PPT Cleaved into the following 5 chains: 1. Substance P 2. Neurokinin A; 3. NKA; Neuromedin L Substance K Neuropeptide K; NPK Neuropeptide gamma C-terminal-flanking peptide; TAC1 recombinant protein
Ordering
For Research Use Only!
Host
E Coli or Yeast or Baculovirus or Mammalian Cell
Purity/Purification
Greater or equal to 85% purity as determined by SDS-PAGE.
Form/Format
Lyophilized or liquid (Format to be determined during the manufacturing process)
Sequence Positions
1-129aa; Full Length
Sequence
MKILVALAVFFLVSTQLFAEEIGANDDLNYWSDWYDSDQIKEELPEPFEHLLQRIARRPKPQQFFGLMGKRDADSSIEKQVALLKALYGHGQISHKRHKTDSFVGLMGKRALNSVAYERSAMQNYERRR
Species
Homo sapiens (Human)
Preparation and Storage
Store at -20 degree C. For extended storage, store at -20 or -80 degree C.

SDS-PAGE

SDS-PAGE
Related Product Information for TAC1 recombinant protein
Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles.
Product Categories/Family for TAC1 recombinant protein

NCBI and Uniprot Product Information

NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
UniProt Accession #
Molecular Weight
42 kDa
NCBI Official Full Name
protachykinin-1 isoform beta
NCBI Official Synonym Full Names
tachykinin, precursor 1
NCBI Official Symbol
TAC1
NCBI Official Synonym Symbols
NK2; NPK; NKNA; TAC2; Hs.2563
NCBI Protein Information
protachykinin-1; PPT; substance K; substance P; neurokinin 1; neurokinin 2; neurokinin A; neuromedin L; tachykinin 2; neuropeptide K; neurokinin alpha; neuropeptide gamma; tachykinin, precursor 1 (substance K, substance P, neurokinin 1, neurokinin 2, neuromedin L, neurokinin alpha, neuropeptide K, neuropeptide gamma)
UniProt Protein Name
Protachykinin-1
Protein Family
UniProt Gene Name
TAC1
UniProt Synonym Gene Names
NKA; NKNA; TAC2; NKA; NPK
UniProt Entry Name
TKN1_HUMAN

NCBI Description

This gene encodes four products of the tachykinin peptide hormone family, substance P and neurokinin A, as well as the related peptides, neuropeptide K and neuropeptide gamma. These hormones are thought to function as neurotransmitters which interact with nerve receptors and smooth muscle cells. They are known to induce behavioral responses and function as vasodilators and secretagogues. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot Description

TAC1: Tachykinins are active peptides which excite neurons, evoke behavioral responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. Belongs to the tachykinin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 7q21-q22

Cellular Component: extracellular space; cell soma; axon; plasma membrane; extracellular region

Molecular Function: protein binding; substance P receptor binding

Biological Process: tachykinin signaling pathway; negative regulation of heart rate; insemination; response to hormone stimulus; response to morphine; response to pain; response to lipopolysaccharide; sensory perception of pain; positive regulation of saliva secretion; synaptic transmission; elevation of cytosolic calcium ion concentration; cell-cell signaling; positive regulation of acute inflammatory response; positive regulation of lymphocyte proliferation; neuropeptide signaling pathway; regulation of blood pressure; positive regulation of stress fiber formation; positive regulation of action potential; inflammatory response; associative learning; detection of abiotic stimulus; positive regulation of synaptic transmission, cholinergic; positive regulation of synaptic transmission, GABAergic; positive regulation of ossification; long-term memory

Research Articles on TAC1

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Product Notes

The TAC1 tac1 (Catalog #AAA967355) is a Recombinant Protein produced from E Coli or Yeast or Baculovirus or Mammalian Cell and is intended for research purposes only. The product is available for immediate purchase. The immunogen sequence is 1-129aa; Full Length. The amino acid sequence is listed below: MKILVALAVF FLVSTQLFAE EIGANDDLNY WSDWYDSDQI KEELPEPFEH LLQRIARRPK PQQFFGLMGK RDADSSIEKQ VALLKALYGH GQISHKRHKT DSFVGLMGKR ALNSVAYERS AMQNYERRR. It is sometimes possible for the material contained within the vial of "Protachykinin-1 (TAC1), Recombinant Protein" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.

Precautions

All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.

Disclaimer

Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.

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