Typical Testing Data/Standard Curve (for reference only)
Mouse A Disintegrin and Metalloproteinase with Thrombospondin Motifs 8 (ADAMTS8) ELISA Kit | ADAMTS8 elisa kit
Mouse A Disintegrin and Metalloproteinase with Thrombospondin Motifs 8 (ADAMTS8) ELISA Kit
Typical Testing Data/Standard Curve (for reference only)
Typical Testing Data/Standard Curve (for reference only)
Principles of the Assay: This kit is an Enzyme-Linked Immunosorbent Assay (ELISA). The plate has been pre-coated with Mouse ADAMTS8 antibody. ADAMTS8 present in the sample is added and binds to antibodies coated on the wells. And then biotinylated Mouse ADAMTS8 Antibody is added and binds to ADAMTS8 in the sample. Then Streptavidin-HRP is added and binds to the Biotinylated ADAMTS8 antibody. After incubation unbound Streptavidin-HRP is washed away during a washing step. Substrate solution is then added and color develops in proportion to the amount of Mouse ADAMTS8. The reaction is terminated by addition of acidic stop solution and absorbance is measured at 450 nm.
NCBI and Uniprot Product Information
NCBI Description
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs, and disrupts angiogenesis in vivo. A number of disorders have been mapped in the vicinity of this gene, most notably lung neoplasms. Reduced expression of this gene has been observed in multiple human cancers and this gene has been proposed as a potential tumor suppressor. [provided by RefSeq, Feb 2016]
Uniprot Description
Has anti-angiogenic properties.
Research Articles on ADAMTS8
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Product Notes
The Mouse ADAMTS8 adamts8 (Catalog #AAA1601171) is an ELISA Kit and is intended for research purposes only. The product is available for immediate purchase. The AAA1601171 ELISA Kit recognizes Mouse ADAMTS8. It is sometimes possible for the material contained within the vial of "A Disintegrin and Metalloproteinase with Thrombospondin Motifs 8 (ADAMTS8), ELISA Kit" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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