Brefeldin A Small Molecule

Brefeldin A

Cat. Num. AAA807965

• Purity: >98%
• Synonyms: Brefeldin A; GEF inhibitor; Cyanaein; Brefeldin A small molecule

• Host: Synthetic
• Purity/Purification: >98%
• Form/Format: White crystalline solid

• Solubility: Soluble to 10 mM in ethanol and to 50 mM in DMSO
• CAS Number: 20350-15-6
• Molecular Formula: C16H24O4
• SMILES: C[C@H]1CCC/C=C/[C@@H]2C[C@@H](C[C@H]2[C@@H](/C=C/C(=O)O1)O)O
• InChI: 1S/C16H24O4/c1-11-5-3-2-4-6-12-9-13(17)10-14(12)15(18)7-8-16(19)20-11/h4,6-8,11-15,17-18H,2-3,5,9-10H2,1H3/b6-4+,
• InChI Key: KQNZDYYTLMIZCT-PNFJWZTBSA-N
• PubChem CID: 5287620
• Preparation and Storage: Store at -20 degree C.

Chemical Structure

(Chemical structure of Brefeldin A (SIH-225), a Inhibits intracellular transport. CAS #: 20350-15-6. Molecular Formula: C16H24O4. Molecular Weight: 280.36 g/mol.)

Related Product Information for Brefeldin A small molecule

Brefeldin A is a reversible inhibitor of proteins from the endoplasmic reticulum (ER) to the golgi. In mammalian and yeast cells, Brefeldin A targets certain GTP-exchange factosr responsible for activating a GTPase called Arf1p (1, 2).

Product Categories/Family for Brefeldin A small molecule

Small Molecules; Inhibitor; Cancer; Apoptosis

References

1. Klausner R.D., Donaldson J.G., Lippincott-Schwartz J. (1992) J Cell Biol. 116(5): 1071-1080. 2. Nebenfuhr A., Ritzenthaler C., and Robinson D.G. (2002) Plant Physiol. 130(3): 1102-1108.