Chemical Structure
(Chemical structure of 2-APB (SIH-316), a TRP blocker. CAS #: 524-95-8. Molecular Formula: C14H16BNO. Molecular Weight: 225.1 g/mol.)
2-APB small molecule
2-APB
Purity
>98%
Synonyms
2-APB; TRP blocker; 2-Aminoethoxydiphenylborane; 2-APB small molecule
Host
Synthetic
Purity/Purification
>98%
Form/Format
White solid
Solubility
Soluble to 100 mM in DMSO and to 10 mM in ethanol
CAS Number
524-95-8
Molecular Formula
C14H16BNO
SMILES
B(C1=CC=CC=C1)(C2=CC=CC=C2)OCCN
InChI
1S/C14H16BNO/c16-11-12-17-15(13-7-3-1-4-8-13)14-9-5-2-6-10-14/h1-10H,11-12,16H2
InChI Key
BLZVCIGGICSWIG-UHFFFAOYSA-N
PubChem CID
1598
PubMed ID
28423644
Preparation and Storage
Store at -20 degree C.
Chemical Structure
(Chemical structure of 2-APB (SIH-316), a TRP blocker. CAS #: 524-95-8. Molecular Formula: C14H16BNO. Molecular Weight: 225.1 g/mol.)
Chemical Structure
(Chemical structure of 2-APB (SIH-316), a TRP blocker. CAS #: 524-95-8. Molecular Formula: C14H16BNO. Molecular Weight: 225.1 g/mol.)
Related Product Information for 2-APB small molecule
2-APB is a chemical that acts to inhibit IP3 receptors (1) and TRP channels (2). It is used to manipulate intracellular release of calcium ions and modify TRP channel activity. There is also evidence that 2-APB acts directly to inhibit gap junctions made of connexin26 or connexin32 (3).
Product Categories/Family for 2-APB small molecule
References
1. Diver J.M., Sage S.O., Rosado J.A. (2001) Cell Calcium. 30(5): 323-329. 2. Xu S.Z., et al. (2005) Br J Pharamcol. 145(4): 320-328. 3. Tao L., and Harris A.L. (2007) Mol Pharmacol. 71(2): 570-579.
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Product Notes
The 2-APB (Catalog #AAA808021) is a Small Molecule produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. It is sometimes possible for the material contained within the vial of "2-APB, Small Molecule" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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