PEX1 sirna
PEX1 siRNA (Mouse)
Gene Names
Pex1; ZWS1; 5430414H02Rik; E330005K07Rik
Reactivity
Mouse
Applications
RNA Interference (RNAi)
Purity
> 97%
Synonyms
PEX1; PEX1 siRNA (Mouse); Peroxisome biogenesis factor 1; Peroxin-1; PEX1 sirna
Host
Synthetic
Reactivity
Mouse
Specificity
PEX1 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Purity/Purification
> 97%
Form/Format
Lyophilized powder
Sequence Length
1284
Applicable Applications for PEX1 sirna
RNA Interference (RNAi)
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse PEX1 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Related Product Information for PEX1 sirna
siRNA to inhibit PEX1 expression using RNA interference
NCBI and Uniprot Product Information
NCBI GI #
NCBI GeneID
NCBI Accession #
NCBI GenBank Nucleotide #
Molecular Weight
136,743 Da
NCBI Official Full Name
peroxisome biogenesis factor 1 isoform 1
NCBI Official Synonym Full Names
peroxisomal biogenesis factor 1
NCBI Official Symbol
Pex1
NCBI Official Synonym Symbols
ZWS1; 5430414H02Rik; E330005K07Rik
NCBI Protein Information
peroxisome biogenesis factor 1
UniProt Protein Name
Peroxisome biogenesis factor 1
Protein Family
UniProt Gene Name
Pex1
UniProt Entry Name
PEX1_MOUSE
Uniprot Description
PEX1: Required for stability of PEX5 and protein import into the peroxisome matrix. Anchored by PEX26 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes required for the import of proteins into peroxisomes. Belongs to the AAA ATPase family. Interacts directly with PEX6. Interacts indirectly with PEX26, via its interaction with PEX6.
Protein type: Hydrolase
Cellular Component: peroxisomal membrane; intracellular membrane-bound organelle; membrane; cytoplasm; peroxisome; cytosol
Molecular Function: protein C-terminus binding; protein complex binding; nucleotide binding; ATPase activity, coupled; lipid binding; ATP binding
Biological Process: protein transport; transport; protein targeting to peroxisome; peroxisome organization and biogenesis; metabolic process; microtubule-based peroxisome localization; protein import into peroxisome matrix
Research Articles on PEX1
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Product Notes
The PEX1 pex1 (Catalog #AAA828379) is a siRNA produced from Synthetic and is intended for research purposes only. The product is available for immediate purchase. The PEX1 siRNA (Mouse) reacts with Mouse and may cross-react with other species as described in the data sheet. AAA Biotech's PEX1 can be used in a range of immunoassay formats including, but not limited to, RNA Interference (RNAi). Researchers should empirically determine the suitability of the PEX1 pex1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process. It is sometimes possible for the material contained within the vial of "PEX1, siRNA" to become dispersed throughout the inside of the vial, particularly around the seal of said vial, during shipment and storage. We always suggest centrifuging these vials to consolidate all of the liquid away from the lid and to the bottom of the vial prior to opening. Please be advised that certain products may require dry ice for shipping and that, if this is the case, an additional dry ice fee may also be required.Precautions
All products in the AAA Biotech catalog are strictly for research-use only, and are absolutely not suitable for use in any sort of medical, therapeutic, prophylactic, in-vivo, or diagnostic capacity. By purchasing a product from AAA Biotech, you are explicitly certifying that said products will be properly tested and used in line with industry standard. AAA Biotech and its authorized distribution partners reserve the right to refuse to fulfill any order if we have any indication that a purchaser may be intending to use a product outside of our accepted criteria.Disclaimer
Though we do strive to guarantee the information represented in this datasheet, AAA Biotech cannot be held responsible for any oversights or imprecisions. AAA Biotech reserves the right to adjust any aspect of this datasheet at any time and without notice. It is the responsibility of the customer to inform AAA Biotech of any product performance issues observed or experienced within 30 days of receipt of said product. To see additional details on this or any of our other policies, please see our Terms & Conditions page.Item has been added to Shopping Cart
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