METRNL sirna

METRNL siRNA (Mouse)

Cat. Num. AAA8228233

• Gene Names: Metrnl; BC019776; 9430048M07Rik
• Reactivity: Mouse
• Applications: RNA Interference (RNAi)
• Purity: > 97%
• Synonyms: METRNL; METRNL siRNA (Mouse); Meteorin-like protein; METRNL sirna

• Host: Synthetic
• Reactivity: Mouse
• Specificity: METRNL siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
• Purity/Purification: > 97%
• Form/Format: Lyophilized powder
• Sequence Length: 311

• Applicable Applications for METRNL sirna: RNA Interference (RNAi)
• Quality Control: Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
• Directions for Use: We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
• Components: We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse METRNL gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for METRNL sirna

siRNA to inhibit METRNL expression using RNA interference

NCBI and Uniprot Product Information

• NCBI GI #: 21450153
• NCBI GeneID: 210029
• NCBI Accession #: NP_659046.1
• NCBI GenBank Nucleotide #: NM_144797.3
• UniProt Accession #: Q8VE43; Q8R1J2
• Molecular Weight: 25,721 Da
• NCBI Official Full Name: meteorin-like protein
• NCBI Official Synonym Full Names: meteorin, glial cell differentiation regulator-like
• NCBI Official Symbol: Metrnl
• NCBI Official Synonym Symbols: BC019776; 9430048M07Rik
• NCBI Protein Information: meteorin-like protein
• UniProt Protein Name: Meteorin-like protein
• Protein Family: Meteorin-like protein
• UniProt Gene Name: Metrnl
• UniProt Entry Name: METRL_MOUSE

Uniprot Description

METRNL: Belongs to the meteorin family.

Protein type: Secreted, signal peptide; Secreted

Cellular Component: extracellular space; extracellular region

Molecular Function: hormone activity

Biological Process: fat cell differentiation; response to muscle activity; negative regulation of inflammatory response; brown fat cell differentiation; response to cold