CD2BP2 blocking peptide

CD2BP2 Blocking Peptide

Cat. Num. AAA8220096

• Gene Names: CD2BP2; LIN1; Snu40; FWP010; U5-52K; PPP1R59
• Reactivity: Human, Monkey
• Applications: Blocking (BL)
• Purity: >85%
• Synonyms: CD2BP2; CD2BP2 Blocking Peptide; KIAA1178; CD2 antigen cytoplasmic tail-binding protein 2; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; U5 snRNP 52K protein; U5-52K; CD2BP2 blocking peptide

• Host: Synthetic
• Reactivity: Human, Monkey
• Purity/Purification: >85%
• Form/Format: Lyophilized powder
• Sequence Length: 341

• Applicable Applications for CD2BP2 blocking peptide: Blocking (BL)
• Quality Control: The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.
• Directions for Use: Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.
• Preparation and Storage: Shipped at 4 degree C. Store at -20 degree C for one year.

Related Product Information for CD2BP2 blocking peptide

The peptide is used to block Anti-CD2BP2 Antibody reactivity.

NCBI and Uniprot Product Information

• NCBI GI #: 343887347
• NCBI GeneID: 10421
• NCBI Accession #: NP_001230575.1
• NCBI GenBank Nucleotide #: NM_001243646.1
• UniProt Accession #: O95400; Q9ULP2; B2RDX2
• Molecular Weight: 37,646 Da
• NCBI Official Full Name: CD2 antigen cytoplasmic tail-binding protein 2
• NCBI Official Synonym Full Names: CD2 (cytoplasmic tail) binding protein 2
• NCBI Official Symbol: CD2BP2
• NCBI Official Synonym Symbols: LIN1; Snu40; FWP010; U5-52K; PPP1R59
• NCBI Protein Information: CD2 antigen cytoplasmic tail-binding protein 2
• UniProt Protein Name: CD2 antigen cytoplasmic tail-binding protein 2
• Protein Family: CD2 antigen cytoplasmic tail-binding protein
• UniProt Gene Name: CD2BP2
• UniProt Synonym Gene Names: KIAA1178; CD2 cytoplasmic domain-binding protein 2; CD2 tail-binding protein 2; U5-52K
• UniProt Entry Name: CD2B2_HUMAN

NCBI Description

This gene encodes a bi-functional protein. In the cytoplasm, the encoded protein binds the cytoplasmic tail of human surface antigen CD2 via its C-terminal GYF domain, and regulate CD2-triggered T lymphocyte activation. In the nucleus, this protein is a component of the U5 small nuclear ribonucleoprotein complex and is involved in RNA splicing. A pseudogene has been identified on chromosome 7. Alternative splicing results in multiple transcript variants but their biological validity has not been determined. [provided by RefSeq, Nov 2008]

Uniprot Description

CD2BP2: Binds the cytoplasmic domain of CD2 through the GYF domain.

Protein type: Spliceosome; RNA processing; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 16p11.2

Cellular Component: nucleoplasm; U4/U6 x U5 tri-snRNP complex; cytoplasm; snRNP U5; nuclear speck; nucleus

Molecular Function: ribonucleoprotein binding; protein binding

Biological Process: nuclear mRNA splicing, via spliceosome; assembly of spliceosomal tri-snRNP; RNA splicing; gene expression